Strain Information | |
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Image | |
BRC No. | RBRC01713 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | 129-Ahr<tm1Yfk> |
Former Common name | AhR(129Sv)+/- mouse |
H-2 Haplotype | |
ES Cell line | CCE/EK.CCE [129S/SvEv-Gpi1<c>] |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor. Mimura J, Yamashita K, Nakamura K, Morita M, Takagi T N, Nakao K, Ema M, Sogawa K, Yasuda M, Katsuki M, Fujii-Kuriyama Y Genes Cells, 2, 645-654 (1997). 9427285 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Ahr | aryl-hydrocarbon receptor | 12 | Ahr | targeted mutation 1, Yoshiaki Fujii-Kuriyama | |||
lacZ | beta-galactosidase (E. coli) | 12 | |||||
neo | neomycin resistance gene (E. coli) | 12 | herpes simplex virus thymidine kinase promoter (HSV tk promoter) | ||||
nls | SV40 large T antigen nuclear localization signal (NLS) | 12 | nls |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | more 12 phenotypes |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | E. coli lacZ, Simian virus 40 Large T antigen nuclear localization signal (NLS), E. coli neo, mouse Ahr genomic DNA, herpes simplex virus thymidine kinase promoter (HSV tk promoter), SV40 T antigen intron and polyadenylation signal |
Research application | Metabolism Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT agrees to include the DEPOSITOR/DEVELOPER as a co-author in any publications resulted by the use of the BIOLOGICAL RESOURCE during the first 2 years after deposition by the DEPOSITOR to the RIKEN BRC. The RECIPIENT should contact the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Yoshiaki Fujii (University of Tsukuba) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |