Strain Data Sheet

RBRC01328

Strain Information

Image
BRC No.RBRC01328
TypeTransgene CongenicCartagena
SpeciesMus musculus
Strain nameC57BL/6J-TgN(Grm2-IL2RA/EGFP)2kyo
Former Common name
H-2 Haplotype
ES Cell line
Background strainC57BL/6J
Appearance
Strain developmentDeveloped by Drs. Dai Watanabe and Shigetada Nakanishi, Kyoto University Faculty of Medicine in 1998.
Strain descriptionThis transgenic mouse strain expresses EGFP and human IL2RA genes under the control of the mGluR promoter.
Colony maintenance
References
Ablation of cerebellar Golgi cells disrupts synaptic integration involving GABA inhibition and NMDA receptor activation in motor coordination.
D Watanabe, H Inokawa, K Hashimoto, N Suzuki, M Kano, R Shigemoto, T Hirano, K Toyama, S Kaneko, M Yokoi, K Moriyoshi, M Suzuki, K Kobayashi, T Nagatsu, R J Kreitman, I Pastan, S Nakanishi
Cell, 95, 17-27 (1998). 9778244

Synaptic integration mediated by striatal cholinergic interneurons in basal ganglia function.
S Kaneko, T Hikida, D Watanabe, H Ichinose, T Nagatsu, R J Kreitman, I Pastan, S Nakanishi
Science, 289, 633-637 (2000). 10915629

Segregation and coactivation of developing neocortical layer 1 neurons.
Takeshi Soda, Ryo Nakashima, Dai Watanabe, Kazunori Nakajima, Ira Pastan, Shigetada Nakanishi
J. Neurosci., 23, 6272-6279 (2003). 12867512

Distinct ontogenic and regional expressions of newly identified Cajal-Retzius cell-specific genes during neocorticogenesis.
Hiroshi Yamazaki, Mariko Sekiguchi, Masako Takamatsu, Yasuto Tanabe, Shigetada Nakanishi
Proc. Natl. Acad. Sci. USA, 101, 14509-14514 (2004). 15452350

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
GFP Green Fluorescent Protein (Aequorea victoria)UN
IL2RA Interleukin-2 receptor α-subunit (human)UNIL2RA mouse metabotropic glutamate receptor 2 (GluR2) promoter, SV40 poly A signals

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • obsolete no phenotypic analysis (MP:0003012)
    • Detailed phenotype data

    Ordering Information

    Donor DNAmouse metabotropic glutamate receptor 2 (GluR2) genomic DNA, human IL-2R alpha cDNA, Jellyfish GFP cDNA, SV40 poly A signals
    Research applicationCell Biology Research
    Fluorescent Proteins/lacZ System
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell, 95, 17-27 (1998).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorShigetada Nakanishi (Kyoto University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data