Strain Information | |
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Image | |
BRC No. | RBRC01328 |
Type | Transgene Congenic |
Species | Mus musculus |
Strain name | C57BL/6J-TgN(Grm2-IL2RA/EGFP)2kyo |
Former Common name | |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6J |
Appearance | |
Strain development | Developed by Drs. Dai Watanabe and Shigetada Nakanishi, Kyoto University Faculty of Medicine in 1998. |
Strain description | This transgenic mouse strain expresses EGFP and human IL2RA genes under the control of the mGluR promoter. |
Colony maintenance | |
References | Distinct ontogenic and regional expressions of newly identified Cajal-Retzius cell-specific genes during neocorticogenesis. Yamazaki H, Sekiguchi M, Takamatsu M, Tanabe Y, Nakanishi S Proc. Natl. Acad. Sci. USA, 101, 14509-14514 (2004). 15452350Segregation and coactivation of developing neocortical layer 1 neurons. Soda T, Nakashima R, Watanabe D, Nakajima K, Pastan I, Nakanishi S J. Neurosci., 23, 6272-6279 (2003). 12867512Synaptic integration mediated by striatal cholinergic interneurons in basal ganglia function. Kaneko S, Hikida T, Watanabe D, Ichinose H, Nagatsu T, Kreitman R J, Pastan I, Nakanishi S Science, 289, 633-637 (2000). 10915629Ablation of cerebellar Golgi cells disrupts synaptic integration involving GABA inhibition and NMDA receptor activation in motor coordination. Watanabe D, Inokawa H, Hashimoto K, Suzuki N, Kano M, Shigemoto R, Hirano T, Toyama K, Kaneko S, Yokoi M, Moriyoshi K, Suzuki M, Kobayashi K, Nagatsu T, Kreitman R J, Pastan I, Nakanishi S Cell, 95, 17-27 (1998). 9778244 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
GFP | Green Fluorescent Protein (Aequorea victoria) | UN | |||||
IL2RA | Interleukin-2 receptor α-subunit (human) | UN | IL2RA | mouse metabotropic glutamate receptor 2 (GluR2) promoter, SV40 poly A signals |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | mouse metabotropic glutamate receptor 2 (GluR2) genomic DNA, human IL-2R alpha cDNA, Jellyfish GFP cDNA, SV40 poly A signals |
Research application | Cell Biology Research Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell, 95, 17-27 (1998).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Shigetada Nakanishi (Kyoto University) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |