Strain Data Sheet


Strain Information

BRC No.RBRC01264
SpeciesMus musculus
Strain nameSM.A-t2dm2saR1A
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Fumihiko Horio, Graduate School of Bioagricultural Sciences, Nagoya University in 2003.
Strain descriptionThis strain carries diabetes-related loci from Chr 2 of A/J backcrossed to SM/J. This strain is thought to carry a causative gene of diabetes in the integration region originating from A/J on chromosome 18. This strain exhibits a clear diabetes phenotype, compared with a control strain. This SM.A-t2dm2saR1A congenic strain was produced by backcrossing of the region between D2Mit11 to D2Mit37 of A/J onto the SM/J.
Colony maintenance
ReferencesDiabetes, 52, 180-186 (2003). 12502510
Diabetologia, 49(3):486-495 (2006). 16447060

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
t2dm2satype 2 diabetes mellitus 22t2dm2sa<A/J>

Ordering Information

Donor DNA
Research applicationDiabetes and Obesity Research
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Diabetologia, 49,486-495 (2006).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
DepositorFumihiko Horio (Nagoya University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
Lab HP (Japanese)

BRC mice in Publications

No Data