Strain Information | |
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Image | |
BRC No. | RBRC01251 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6-Tg(EIF1A-FLP)14Mim/MimRbrc |
Former Common name | FLP14; FLP14 mouse |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6NCrlCrlj |
Appearance | |
Strain development | Developed by Dr. Masami Mishina, The Tokyo University. |
Strain description | This transgenic mice express FLP recombinase with the SV40 large T antigen nuclear localization signal at its amino terminus under the control of human eukaryotic translation initiation factor 1 promoter. |
Colony maintenance | |
References | Flp recombinase transgenic mice of C57BL/6 strain for conditional gene targeting. Takeuchi T, Nomura T, Tsujita M, Suzuki M, Fuse T, Mori H, Mishina M Biochem. Biophys. Res. Commun., 293, 953-957 (2002). 12051751 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
FLP | yeast flippase recombinase | UN | FLP | human elongation factor 1 alpha (EF-1 alpha) promoter | |||
nls | SV40 large T antigen nuclear localization signal (NLS) | UN | nls | ||||
poly A | human granulocyte colony-stimulating facter gene polyAdenylation signal sequence | UN | poly A |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | human EF1-alpha promoter, SV40 large T antigen nuclear localization signal, yeast flp recombinase, human granulocyte colony-stimulating facter gene poly adenylation signal sequence |
Research application | Cell Biology Research FLP/frt system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochem. Biophys. Res. Commun., 293, 953-957 (2002).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Masayoshi Mishina (The University of Tokyo) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |