Strain Data Sheet

RBRC01155

Strain Information

Image
BRC No.RBRC01155
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6-Tg(CAG-Akt1/EGFP)2Tssk/TsskRbrc
Former Common nameA2, EGFP-Akt-2 transgenic mouse
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain development
Strain description
Colony maintenance
References
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1.
Nishio M, Watanabe K, Sasaki J, Taya C, Takasuga S, Iizuka R, Balla T, Yamazaki M, Watanabe H, Itoh R, Kuroda S, Horie Y, Forster I, Mak T W, Yonekawa H, Penninger J M, Kanaho Y, Suzuki A, Sasaki T
Nature Cell Biol., 9, 36-44 (2007). 17173042

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Akt1thymoma viral proto-oncogene 1UNAkt1
  • colorectal cancer(MedGEN)

  • Cowden syndrome 6(MedGEN)

  • hereditary breast carcinoma(MedGEN)
    • more 2 Diseases
  • ovarian neoplasm(MedGEN)

  • Proteus syndrome(MedGEN)
    • EGFPGreen Fluorescent Protein (Aequorea victoria)UNEGFPCAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)
  • colorectal cancer(MedGEN)

  • Cowden syndrome 6(MedGEN)

  • hereditary breast carcinoma(MedGEN)
    • more 2 Diseases
  • ovarian neoplasm(MedGEN)

  • Proteus syndrome(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    Donor DNACAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), Akt (serin threonine kinase) cDNA, Jellyfish GFP cDNA
    Research applicationCancer Research
    Cell Biology Research
    Fluorescent Proteins/lacZ System
    General Purpose
    Immunology and Inflammation Research
    Metabolism Research
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nature Cell Biol., 9, 36-44 (2007). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT is requested to submit the abstract of the research project to the DEPOSITOR, Dr. Sasaki T.
    DepositorTakehiko Sasaki (Akita University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. CAGGS MTA (English)
    5. Acceptance of responsibility for living modified organism (Japanese / English)
    Lab HP (Japanese)
    Genotyping protocol -PCR-
    Mouse of the Month Nov 2007

    BRC mice in Publications

    No Data