Strain Data Sheet

RBRC01142

Strain Information

Image
BRC No.RBRC01142
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameICR.Cg-Tg(CAG-cat,-Notch1)1Ysa/YsaRbrc
Former Common nameCAG-CAT-Notch1
H-2 Haplotype
ES Cell line
Background strainJcl:MCH(ICR)
Appearancealbino [c/c]
Strain development開発年：2002年開発者：相賀裕美子先生機関名：国立遺伝学研究所tg マウス作出時の受精卵の系統名、亜系統名を含むフルネームJC1:B6C3F1 (クレア）交配に供したICRの購入元：クレア（MCH)
Strain descriptionCre recombinase 発現マウスとの交配により、Cre発現細胞で活性型Notch1が発現する。
Colony maintenanceSibling Mating
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Notch1 Notch gene homolog 1 (Drosophila)UNNotch1
cat E. coli chloramphenicol acetyltransferase (CAT)UN CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)
loxP phage P1 loxPUNloxP
loxP phage P1 loxPUNloxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    供与核酸CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), phage P1 loxP sites, E. coli chloramphenicol acetyltransferase (CAT) gene, poly A, Notch1 intracellular domain cDNA, poly A
    Research applicationCre/loxP system
    提供条件研究成果の公表にあたって謝辞の表明を必要とする。
    Depositor相賀　裕美子（国立遺伝学研究所）
    Strain Status凍結胚のアイコン凍結胚
    凍結精子のアイコン凍結精子
    Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
    凍結精子を1ヶ月以内に提供可能
    凍結胚を1ヶ月以内に提供可能
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. CAGGS MTA (English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)
    Saga Lab HP
    Genotyping protocol -PCR-

    BRC mice in Publications

    Kratsios P, Catela C, Salimova E, Huth M, Berno V, Rosenthal N, Mourkioti F.
    Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart.
    Circ Res 106(3) 559-72(2010) 20007915