Strain Information | |
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Image | |
BRC No. | RBRC01131 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6-Tg(CAG-p35)1Miur/Rbrc |
Former Common name | CAG-loxP-p35 Tg mice |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | black |
Strain development | Developed by Hisahara S, Araki T and Miura M at Osaka Univ. Graduate School Med. in 2000. The mice were generated by using C57BL/6 fertilized eggs. |
Strain description | This transgenic mouse expresses the baculovirus anti-apoptotic protein p35 in oligodendrocytes through the Cre-loxP system. |
Colony maintenance | Both hemizygous and homozygous transgenic mice can be bred as well as wild-type C57BL/6 mice. |
References | EMBO J., 19, 341-348 (2000). 10654933 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxPUNloxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxPUNloxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)UNneo; neomycin;CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter p35baculovirus anti-apoptotic protein p35UNp35 |
Ordering Information | |
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Donor DNA | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), baculovirus anti-apoptotic protein p35, E. coli neo, phage P1 loxP, SV40 poly A |
Research application | Cre/loxP system |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EMBO J., 19, 341-348 (2000).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The material shall be used for teaching or not-for-profit research purposes only for the research described within this MTA. |
Depositor | Masayuki Miura (The University of Tokyo) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |