Strain Data Sheet
RBRC01073
Information1 | |
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| Image | |
| BRC No. | RBRC01073 |
| Type | Congenic |
| Species | Mus musculus |
| Strain name | SM.A-(D2Mit295-D2Mit281)/Rbrc |
| Former Common name | SM.A-t2dm2sa |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Developed by Drs. Misato Kobayashi and Fumihiko Horio, Graduate School of Bioagricultural Sciences, Nagoya University in 2003. This SM.A-t2dm2sa congenic strain was produced by 6 backcrossing of the region between D2Mit295 to D2Mit281 of A/J onto the SM/J. |
| Strain description | This strain carries diabetes-related loci from Chr 2 of A/J backcrossed to SM/J. This strain is useful for helping to understand of the complex gene-gene interaction and model of human type 2 diabetes. This SM.A-t2dm2sa congenic strain was produced by 6 backcrossing of the region between D2Mit295 to D2Mit281 of A/J onto the SM/J. |
| Colony maintenance | |
| References | Diabetologia, 49(3):486-495 (2006). 16447060 Physiol Genomics, 35(1): 65-74 (2008). 18628340 Diabetes, 52, 180-186 (2003). 12502510 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter t2dm2satype 2 diabetes mellitus 22t2dm2sa<A/J> |
Information2 | |
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| Donor DNA | |
| Research application | Diabetes and Obesity Research covid19_progression |
| Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Diabetologia, 49,486-495 (2006).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR. |
| Depositor | Fumihiko Horio (Nagoya University) |
| Strain Status |  Frozen embryos |
| Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
| Additional Info. | Necessary documents for ordering:
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BRC mice in Publications |
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