Strain Data Sheet

RBRC01059

update : 2024-04-19

Strain Information
Image
BRC No.	RBRC01059
Type	Inbred
Species	Mus musculus
Strain name	NC
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance	agouti brown [A/A b/b C/C D/D S/S]
Strain development	NCマウスは1955年に日本在来種のマウスから近藤　恭司先生によって純系化された。当時の機関は名古屋大学農学部家畜育種学講座で、その後の大学院重点化により、大学院生命農学研究科応用遺伝・生理学講座となった。
Strain description	ヒフ病モデル
Colony maintenance	兄妹交配、繁殖効率：A
References	JIkken Doubutsu, 6, 107-112 (1957).

Health Report
Examination Date / Room / Rack	2024/02/26Room:4-BRack:J 2023/11/27Room:4-BRack:J 2023/08/28Room:4-BRack:J 2023/05/29Room:4-BRack:J 2023/02/27Room:4-BRack:J 2022/11/29Room:4-BRack:J 2022/08/29Room:4-BRack:J 2022/05/31Room:4-BRack:J

Gene
Gene info	Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Derm1dermititis 19Derm1NC/Nga

Ordering Information
供与核酸
Research application	Dermatology Research
提供条件	条件を付加しない。
Depositor	並河　鷹夫（名古屋大学）
Strain Status	生体凍結胚
Strain Availability	凍結胚を1ヶ月以内に提供可能生体マウスを1~3ヶ月以内に提供可能
Additional Info.	Necessary documents for ordering: Order form (Japanese / English) Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

BRC mice in Publications

Chiu YH, Wu YW, Hung JI, Chen MC. Epigallocatechin gallate/L-ascorbic acid-loaded poly-γ-glutamate microneedles with antioxidant, anti-inflammatory, and immunomodulatory effects for the treatment of atopic dermatitis. Acta Biomater 130 223-233(2021) 34087444 Chen MC, Chen CS, Wu YW, Yang YY. Poly-γ-Glutamate microneedles as transdermal immunomodulators for ameliorating atopic dermatitis-like skin lesions in Nc/Nga mice. Acta Biomater 114 183-192(2020) 32688089 F Zhuo, MAS Abourehab, Z Hussain. Hyaluronic Acid Decorated Tacrolimus-Loaded Nanoparticles: Efficient Approach to Maximize Dermal Targeting and Anti-dermatitis Efficacy. Carbohydrate Polymers () Hussain Z, Katas H, Mohd Amin MC, Kumolosasi E, Buang F, Sahudin S. Self-assembled polymeric nanoparticles for percutaneous co-delivery of hydrocortisone/hydroxytyrosol: an ex vivo and in vivo study using an NC/Nga mouse model. Int J Pharm 444(1-2) 109-19(2013) 23337632 Hussain Z, Katas H, Amin MC, Kumulosasi E, Sahudin S. Antidermatitic perspective of hydrocortisone as chitosan nanocarriers: an ex vivo and in vivo assessment using an NC/Nga mouse model. J Pharm Sci 102(3) 1063-75(2013) 23303620 Knitlova J, Hajkova V, Voska L, Elsterova J, Obrova B, Melkova Z. Development of eczema vaccinatum in atopic mouse models and efficacy of MVA vaccination against lethal poxviral infection. PLoS One 9(12) e114374(2014) 25486419 Hussain Z, Katas H, Mohd Amin MC, Kumolosasi E. Efficient immuno-modulation of TH1/TH2 biomarkers in 2,4-dinitrofluorobenzene-induced atopic dermatitis: nanocarrier-mediated transcutaneous co-delivery of anti-inflammatory and antioxidant drugs. PLoS One 9(11) e113143(2014) 25396426 Yang Z, Liu M, Wang W, Wang Y, Cao B, Gao Y, Chen H, Li T. Pseudolaric acid B attenuates atopic dermatitis-like skin lesions by inhibiting interleukin-17-induced inflammation. Sci Rep 7(1) 7918(2017) 28801611

BRC mice in Publications

Chiu YH, Wu YW, Hung JI, Chen MC.
Epigallocatechin gallate/L-ascorbic acid-loaded poly-γ-glutamate microneedles with antioxidant, anti-inflammatory, and immunomodulatory effects for the treatment of atopic dermatitis.
Acta Biomater 130 223-233(2021) 34087444

Chen MC, Chen CS, Wu YW, Yang YY.
Poly-γ-Glutamate microneedles as transdermal immunomodulators for ameliorating atopic dermatitis-like skin lesions in Nc/Nga mice.
Acta Biomater 114 183-192(2020) 32688089

F Zhuo, MAS Abourehab, Z Hussain.
Hyaluronic Acid Decorated Tacrolimus-Loaded Nanoparticles: Efficient Approach to Maximize Dermal Targeting and Anti-dermatitis Efficacy.
Carbohydrate Polymers ()

Hussain Z, Katas H, Mohd Amin MC, Kumolosasi E, Buang F, Sahudin S.
Self-assembled polymeric nanoparticles for percutaneous co-delivery of hydrocortisone/hydroxytyrosol: an ex vivo and in vivo study using an NC/Nga mouse model.
Int J Pharm 444(1-2) 109-19(2013) 23337632

Hussain Z, Katas H, Amin MC, Kumulosasi E, Sahudin S.
Antidermatitic perspective of hydrocortisone as chitosan nanocarriers: an ex vivo and in vivo assessment using an NC/Nga mouse model.
J Pharm Sci 102(3) 1063-75(2013) 23303620

Knitlova J, Hajkova V, Voska L, Elsterova J, Obrova B, Melkova Z.
Development of eczema vaccinatum in atopic mouse models and efficacy of MVA vaccination against lethal poxviral infection.
PLoS One 9(12) e114374(2014) 25486419

Hussain Z, Katas H, Mohd Amin MC, Kumolosasi E.
Efficient immuno-modulation of TH1/TH2 biomarkers in 2,4-dinitrofluorobenzene-induced atopic dermatitis: nanocarrier-mediated transcutaneous co-delivery of anti-inflammatory and antioxidant drugs.
PLoS One 9(11) e113143(2014) 25396426

Yang Z, Liu M, Wang W, Wang Y, Cao B, Gao Y, Chen H, Li T.
Pseudolaric acid B attenuates atopic dermatitis-like skin lesions by inhibiting interleukin-17-induced inflammation.
Sci Rep 7(1) 7918(2017) 28801611

Strain Information

Health Report

Gene

Ordering Information

BRC mice in Publications