Strain Information | |
---|---|
Image | |
BRC No. | RBRC01055 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | B6;129P2-Ski<tm1Cco> |
Former Common name | Ski Knockout mouse |
H-2 Haplotype | |
ES Cell line | E14.1 [129P2/OlaHsd] |
Background strain | C57BL/6NJcl |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Mice lacking the ski proto-oncogene have defects in neurulation, craniofacial, patterning, and skeletal muscle development. Berk M, Desai S Y, Heyman H C, Colmenares C Genes Dev., 11, 2029-2039 (1997). 9284043 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |||||||
---|---|---|---|---|---|---|---|
Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Ski | ski sarcoma viral oncogene homolog (avian) | 4 | Ski | targeted mutation 1, Clemencia Colmenares | |||
neo | neomycin resistance gene (E. coli) | 4 | herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Phenotype | |
---|---|
Annotation by Mammalian phenotyhpe ontology | more 35 phenotypes |
Detailed phenotype data |
Ordering Information | |
---|---|
Donor DNA | E. coli neo, mouse Sloan-Ketterong viral oncongene homolog genome DNA, herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Research application | Developmental Biology Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Dev., 11, 2029-2039 (1997). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. |
Depositor | Clemencia Colmenares (The Cleveland Clinic Foundation) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
---|
No Data |