Strain Data Sheet

RBRC01045

Strain Information

Image
BRC No.RBRC01045
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Mybl2<tm1Sis>/Rbrc
Former Common nameB-Myb Knockout mice
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
B-myb is required for inner cell mass formation at an early stage of development.
Y Tanaka, N P Patestos, T Maekawa, S Ishii
J. Biol. Chem., 274, 28067-28070 (1999). 10497154

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Mybl2
MGI:101785		myeloblastosis oncogene-like 22Mybl2<tm1Sis>
MGI:2445746		targeted mutation 1, Shunsuke Ishii
neo neomycin resistance gene (E. coli)2

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • abnormal inner cell mass morphology (MP:0002718)

  • embryonic lethality between implantation and somite formation, complete penetrance (MP:0011096)
    • Detailed phenotype data

    Ordering Information

    Donor DNAE. coli neo, mouse myeloblastosis oncogene-like2 genomic DNA
    Research applicationCell Biology Research
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Biol. Chem., 274, 28067-28070 (1999).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorShunsuke Ishii (RIKEN)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data