Strain Data Sheet

RBRC00906

Strain Information

Image
BRC No.RBRC00906
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6-Tg(pLck-EGFP)1Naka/Rbrc
Former Common nameplck-GFP Tg
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearanceblack [(a/a B/B C/C)]
Strain development2001年、中山俊憲先生、千葉大学大学院免疫細胞医学
Strain descriptionproximal lck promoterの制御のもとでEGFPを発現するマウス。
Colony maintenance野生型マウスと同様。
References
Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activity.
Shimizu C, Kawamoto H, Yamashita M, Kimura M, Kondou E, Kaneko Y, Okada S, Tokuhisa T, Yokoyama M, Taniguchi M, Katsura Y, Nakayama T
Int. Immunol., 13, 105-117 (2001). 11133839

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
GFPGreen Fluorescent Protein (Aequorea victoria)UNlck proximal promoter, human growth hormone enhancer
  • severe combined immunodeficiency due to LCK deficiency(MedGEN)
    • GHGrowth hormone polyA (human)UNGH
  • severe combined immunodeficiency due to LCK deficiency(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    供与核酸proximal lck promoter, Jellyfish GFP cDNA, human GH enhancer
    Research applicationFluorescent Proteins/lacZ System
    Immunology and Inflammation Research
    提供条件利用者は事前に寄託者の提供承諾書を得る。研究成果の公表にあたって寄託者の指定する文献を引用する。Int. Immunol., 13(1) 105-117 (2001). 利用者が本件リソース寄託後2年以内に理研BRCより提供を受けて得た研究成果の発表は寄託者(開発者)との共著とする。利用者が本件リソースを使用して得られた研究成果に基づき特許等の申請、及び事業活動を行う場合は、寄託者と別途協議を行う。
    Depositor中山　俊憲（千葉大学）
    Strain Status凍結胚のアイコン凍結胚
    Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
    凍結胚を1ヶ月以内に提供可能
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)
    Lab HP
    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data