Strain Information | |
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Image | |
BRC No. | RBRC00889 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | STOCK Spen<tm1Hon>/HonRbrc |
Former Common name | MINT-KO (ICR background) |
H-2 Haplotype | |
ES Cell line | E14 [129P2/OlaHsd] |
Background strain | Slc:ICR |
Appearance | albino |
Strain development | |
Strain description | |
Colony maintenance | |
References | Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway. Kuroda K, Han H, Tani S, Tanigaki K, Tun T, Furukawa T, Taniguchi Y, Kurooka H, Hamada Y, Toyokuni S, Honjo T Immunity, 18, 301-312 (2003). 12594956 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Spen | spen family transcription repressor | 4 | Spen | targeted mutation 1, Tasuku Honjo | |||
neo | neomycin resistance gene (E. coli) | 4 | mouse phosphoglycerate kinase promoter (PGK promoter) |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse Spen genomic DNA |
Research application | Developmental Biology Research Immunology and Inflammation Research Internal/Organ Research |
Specific Term and Conditions | 1) The RECIPIENT shall use the BIOLOGICAL RESOURCE only for academic research for the purpose of publishing the research results. 2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR and a citation of the following literature(s) designated by the DEPOSITOR are requested. Immunity 18, 301-312 (2003). 3) RECIPIENT shall notify the PROVIDER upon filing a patent application claiming modification of the BIOLOGICAL RESOURCE or method(s) of manufacture or use(s) of the BIOLOGICAL RESOURCE. |
Depositor | Tasuku Honjo (Kyoto University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |