Strain Data Sheet

RBRC00872

Strain Information

Image
BRC No.RBRC00872
TypeChromosomal Aberration
SpeciesMus musculus
Strain nameSTOCK XO Eda<Ta>/O/Rbrc
Former Common nameXO
H-2 Haplotype
ES Cell line
Background strain
Appearanceagouti with mosaic striped coat [X<Ta>/X]
agouti with tabby [X<Ta>/X<Ta>, X<Ta>/Y]
Strain developmentDeposited by Dr. Nobuo Takagi, Hokkaido University.
Strain description父由来Xを持つ個体の作成 (正常雄はX<M>Yであるのに対し、XOマウスはX<p>Oである) 。XOのみならず、OY胚も得られる。
Colony maintenanceWild♀とTabby♂を交配。Tabby♀がXO。次代ではTabby♀とWild♂を交配。Wild♀がXOこれを交互に繰り返す。
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Eda
MGI:1195272		ectodysplasin-AXEda<Ta>
MGI:1856197		tabby
  • tooth agenesis, selective, X-linked, 1(MedGEN)

  • X-linked hypohidrotic ectodermal dysplasia(DisGeNET, MedGEN)

    • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
  • abnormal coat appearance (MP:0001510)

  • abnormal coat/ hair morphology (MP:0000367)

  • abnormal coat/hair pigmentation (MP:0002075)

  • abnormal cornea epithelium morphology (MP:0006000)

  • abnormal cornea morphology (MP:0001312)
    • more 45 phenotypes
  • abnormal eye morphology (MP:0002092)

  • abnormal eyelid margin morphology (MP:0013745)

  • abnormal eyelid morphology (MP:0001340)

  • abnormal guard hair morphology (MP:0000397)

  • abnormal hair follicle development (MP:0003704)

  • abnormal hair follicle melanocyte morphology (MP:0004381)

  • abnormal hair follicle pheomelanosome pheomelanin content (MP:0006370)

  • abnormal hair growth (MP:0002073)

  • abnormal hair texture (MP:0002074)

  • abnormal lateral nasal gland morphology (MP:0013582)

  • abnormal molar cusp morphology (MP:0030457)

  • abnormal molar root morphology (MP:0030494)

  • abnormal nasal cavity morphology (MP:0002237)

  • abnormal nasal gland morphology (MP:0013580)

  • abnormal nose morphology (MP:0002233)

  • abnormal palatal rugae morphology (MP:0009652)

  • abnormal respiratory system morphology (MP:0002132)

  • abnormal skeleton morphology (MP:0005508)

  • abnormal skin pigmentation (MP:0002095)

  • abnormal tail morphology (MP:0002111)

  • abnormal tail ring morphology (MP:0012078)

  • abnormal tail tip morphology (MP:0013177)

  • abnormal vibrissa number (MP:0009003)

  • absent Meibomian glands (MP:0006236)

  • absent guard hair (MP:0006365)

  • absent hair follicle pheomelanosome pheomelanin (MP:0006371)

  • absent vibrissae (MP:0001284)

  • absent zigzag hairs (MP:0006366)

  • blepharitis (MP:0005251)

  • conjunctivitis (MP:0001852)

  • cornea opacity (MP:0001314)

  • cornea vascularization (MP:0005542)

  • corneal limbitis (MP:0013478)

  • decreased zigzag hair amount (MP:0008538)

  • eye inflammation (MP:0001851)

  • focal hair loss (MP:0000418)

  • hairless tail (MP:0010233)

  • increased incidence of corneal inflammation (MP:0001313)

  • irregular coat pigmentation (MP:0000372)

  • kinked tail (MP:0000585)

  • narrow eye opening (MP:0005287)

  • striated fur (MP:0009659)

  • thin epidermis (MP:0001218)

  • thin skin (MP:0001199)

  • transverse fur striping (MP:0010231)
    • Detailed phenotype data

    Ordering Information

    供与核酸
    Research application
    提供条件条件を付加しない。
    Depositor高木　信夫（北海道大学）
    Strain Status凍結胚のアイコン凍結胚
    Strain Availability生体マウスを3~6ヶ月以内に提供可能
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    Miura K, Murata C, Harikae K, Suzuki H, Kanai-Azuma M, Kurohmaru M, Tsunekawa N, Kanai Y.
    Defects in the first wave of folliculogenesis in mouse XO ovaries.
    J Reprod Dev 63(3) 333-338(2017) 28392504