Strain Data Sheet

RBRC00843

Strain Information

Image
BRC No.RBRC00843
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2-Maf<tm1Mym>/2Rbrc
Former Common name44A, c-Maf/2 KO
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strainC57BL/6J
Appearance
Strain development1998年、筑波大学　基礎医学系　解剖学・発生学研究室で川内紫真子先生が開発。高橋智先生が責任者
Strain descriptionホモ欠損マウスは、生後３日以内に死亡 (原因不明) 。CD4 Th2 細胞においてIL-4の産生が欠損している。目の水晶体の線維細胞の形成が不全。
Colony maintenanceへテロマウスで維持。
ReferencesJ. Biol. Chem., 274, 19254-19260 (1999). 10383433

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Mafavian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog8Maf<tm1Mym>targeted mutation 1, Masayuki Yamamotoc-Maf

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
lacZbeta-galactosidase (E. coli)8

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)8neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Ordering Information

供与核酸mouse c-Maf genomic DNA, E. coli neomycin phosphotransferase, E. coli lacZ, herpes simplex virus thymidine kinase promoter (HSV tk promoter)
Research applicationImmunology and Inflammation Research
Sensorineural Research
提供条件条件を付加する。利用者は事前に寄託者の提供承諾書を得る。
共同研究
Depositor高橋　智（国立大学法人筑波大学）
Strain Status凍結胚のアイコン凍結胚
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)
Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

No Data