Strain Data Sheet

RBRC00819

Strain Information

Image
BRC No.RBRC00819
TypeTransgene CongenicCartagena
SpeciesMus musculus
Strain nameC57BL/6-Tg(Zic1tr/iresLacZ)1Arg
Former Common nameTR9K
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain development
Strain descriptionDorsal spinal coed is marked by LacZ expression.
Colony maintenance
References
Zic1 promotes the expansion of dorsal neural progenitors in spinal cord by inhibiting neuronal differentiation.
Aruga J, Tohmonda T, Homma S, Mikoshiba K
Dev. Biol., 244, 329-341 (2002). 11944941

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
IRESinternal ribosomal entry site (EMCV)UN
  • craniosynostosis 6(MedGEN)

  • structural brain anomalies with impaired intellectual development and craniosynostosis(MedGEN)
  • Zic1zinc finger protein of the cerebellum 1UNZic1
  • craniosynostosis 6(MedGEN)

  • structural brain anomalies with impaired intellectual development and craniosynostosis(MedGEN)
  • lacZbeta-galactosidase (E. coli)UN
  • craniosynostosis 6(MedGEN)

  • structural brain anomalies with impaired intellectual development and craniosynostosis(MedGEN)
  • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
  • Detailed phenotype data

    Ordering Information

    Donor DNAmouse zinc finger protein of the cerebellum 1(nervous system specific transcription factor) Zic1 genomic DNA, Encephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), E. coli lacZ
    Research applicationDevelopmental Biology Research
    Neurobiology Research
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Dev. Biol., 244, 329-341 (2002). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorJun Aruga (RIKEN)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)
    Lab HP

    BRC mice in Publications

    No Data