Strain Data Sheet

RBRC00805

Strain Information

Image
BRC No.RBRC00805
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129S-Hoxc<tm1Nogu>/NoguRbrc
Former Common nameHox C cluster Knockout mice
H-2 Haplotype
ES Cell line
Background strainC57BL/6NJcl
Appearanceblack [a/a B/B C/C]
Strain developmentDeveloped by Dr. Hirofumi Suemori, Meiji Institute of Health Science in 1996.
Strain descriptionB6;129S-Hoxc<tm1Nogu>. Hoxc gene deficient mice. Homozygous mutant mice are embryonic lethal.
Colony maintenancebackcross to C57BL/6N (Heterozygote x C57BL/6NJcl)
ReferencesDev Biol., 220, 333-342 (2000). 10753520

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Hoxchomeo box C cluster15Hoxc<tm1Nogu>targeted mutation 1, Shigeru NoguchiHox-3, Hox-6

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP15loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
puropuromycin acyltransferase (Streptomyces alboniger)15puro

Ordering Information

供与核酸mouse homeo box C cluster genomic DNA, PEF1a (elongation factor 1a promoter), Phage P1 loxP, Streptomyces alboniger puromycin-resistance gene
Research application
提供条件条件を付加する。
研究成果の公表にあたって寄託者の指定する文献を引用する。Del. Biol., 220, 333-342 (2000).
Depositor末盛　博文（(財)神奈川科学技術アカデミー）
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結精子を1ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

Schorderet P, Duboule D.
Structural and functional differences in the long non-coding RNA hotair in mouse and human.
PLoS Genet 7(5) e1002071(2011) 21637793

Tschopp P, Fraudeau N, Béna F, Duboule D.
Reshuffling genomic landscapes to study the regulatory evolution of Hox gene clusters.
Proc Natl Acad Sci U S A 108(26) 10632-7(2011) 21670281