Strain Information | |
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Image | |
BRC No. | RBRC00785 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6-Tg(GOFMBD)2Imeg |
Former Common name | Oct-MBDGFP#2, TgN(GOFMBD)2Imeg |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | black |
Strain development | Developed by Kuniya Abe, RIKEN BioResrouce Center (Institute of Molecular Embryology and Genetics) in 2001. |
Strain description | GOFMBD transgenic mice expressing MBD (methylated DNA bifing domain) and GFP fusion protein under the control of the Oct-4 promoter (GOF18). GODMBD lines containing a proximal enhancer (PE): Line 1, Line 2, Line 4, Line 5. deltaMBD lines lacking a proximal enhancer (PE): Line 1 (RBRC00788), Line 2 (RBRC00789), Line 3 (RBRC00790). |
Colony maintenance | Carrier x Carrier [or Crossing to C57BL/6JJcl] |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
MBD (methylated DNA binding domain) | UN | ||||||
GFP | Green Fluorescent Protein (Aequorea victoria) | UN | Oct 3/4 promoter |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | Oct3/4 promoter, MBD(methylated DNA binding domain) cDNA, Jellyfish GFP cDNA |
Research application | Cell Biology Research Developmental Biology Research Fluorescent Proteins/lacZ System Genetics Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The DEPOSITOR should be a co-author in articles when the users publish their data using these mice for 2 year after provided to the RIKEN BRC. Users should contact the DEPOSITOR in the case of application for any patents with the results from these mice. |
Depositor | Kuniya Abe (RIKEN) |
Strain Status | Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering:
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BRC mice in Publications |
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No Data |