Strain Information | |
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Image | |
BRC No. | RBRC00690 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129P2-Glb1<tm11Azzo>/Rbrc |
Former Common name | beta-galactosidase Knockout mice |
H-2 Haplotype | |
ES Cell line | E14 [129P2/OlaHsd] |
Background strain | C57BL/6JJcl |
Appearance | black |
Strain development | 1997, Kunihiko Suzuki, M.D.Departments of neurology and Psychiatry, University of North Carolina, Chapel Hill, NC 27599-7250, U.S.A. |
Strain description | Neurobiology Research, Metabolic Defects, Lysosomal Storage Disease |
Colony maintenance | Heterozygote X Heterozygote |
References | Generalized CNS disease and massive GM1-ganglioside accumulation in mice defective in lysosomal acid beta-galactosidase. Hahn C N, del Pilar Martin M, Schroder M, Vanier M T, Hara Y, Suzuki K, Suzuki K, d'Azzo A Hum. Mol. Genet., 6, 205-211 (1997). 9063740 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Glb1 | galactosidase, beta 1 | 9 | Glb1 | targeted mutation 1, Alessandra d’Azzo | |||
neo | neomycin resistance gene (E. coli) | 9 | mouse phosphoglycerate kinase promoter (PGK promoter) |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse beta-galactosidase genomic DNA |
Research application | Metabolism Research Neurobiology Research |
Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
Depositor | Junko Matsuda (Tokushima University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |