Strain Data Sheet

RBRC00609

Strain Information

Image
BRC No.RBRC00609
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameC57BL/10Snf-Rim4/+
Former Common nameRecombination induced mutation 4 (Rim4)
H-2 Haplotype
ES Cell line
Background strain
Appearanceblack
Strain developmentDeveloped by Toshihiko Shiroishi, National Institute of Genetics. C57BL/10 background.
Strain descriptionSpontaneous mouse mutant, Recombination-induced mutation 4, Rim4. The mutation is mapped on Chr6, and the critical region contains the insertion of a 6.5 Mb genomic fragment derived from Chr8. The insertion fragment is syntenic to the human Chr4 4q32-q34, which is responsible for a human chromosomal disorder 4q+.
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Rim4recombination induced mutation 46Rim4

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal cervical vertebrae morphology(MP:0003048)

  • abnormal limb development(MP:0006279)

  • abnormal lumbar vertebrae morphology(MP:0003049)

  • abnormal pollex morphology(MP:0010772)

  • abnormal skeleton morphology(MP:0005508)
  • more 21 phenotypes
  • abnormal talus morphology(MP:0005109)

  • abnormal tibia morphology(MP:0000558)

  • abnormal vertebral transverse process morphology(MP:0004600)

  • abnormal zone of polarizing activity morphology(MP:0012528)

  • abnormal zygomatic bone morphology(MP:0005270)

  • absent vertebral spinous process(MP:0004606)

  • clavicle hypoplasia(MP:0004337)

  • domed cranium(MP:0000440)

  • hemimelia(MP:0008985)

  • mirror image duplication(MP:0009470)

  • patent ductus arteriosus(MP:0003139)

  • polydactyly(MP:0000562)

  • postnatal growth retardation(MP:0001732)

  • preaxial polydactyly(MP:0009743)

  • premature death(MP:0002083)

  • renal/urinary system phenotype(MP:0005367)

  • sacral vertebral transformation(MP:0004617)

  • scoliosis(MP:0000161)

  • short tibia(MP:0002764)

  • triphalangia(MP:0008829)

  • ventricular septal defect(MP:0010402)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationDevelopmental Biology Research
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorToshihiko Shiroishi (National Institute of Genetics)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data