Strain Data Sheet

RBRC00455

Strain Information

Image
BRC No.RBRC00455
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129P2-Skp2<tm1Kin>
Former Common nameSkp2 Knockout mice
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearanceblack [a/a B/B C/C]
Strain development＞10世代　C57BL/6に戻し交配
Strain descriptionB6.129P2-Skp2<tm1Kin>. Skp2 gene knock-out mice. Homozygous mutant mice are viable, but show reduced growth rate and increased apoptosis of cells.
Colony maintenance繁殖成績が低い形態の異常・奇形がある
ReferencesEMBO J., 19, 2069-2081 (2000). 10790373

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Skp2S-phase kinase-associated protein 2 (p45)15Skp2<tm1Kin>targeted mutation 1, Kei-ichi NakayamaFBXL1

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)15neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

供与核酸PGK promoter (mouse phosphoglycerate kinase gene promoter), Neomycin resistance gene (neomycin phosphotransferase II (nptll) gene of the transposon Tn5 in Escherichia coli K12), PGK polyA (mouse phosphoglycerate kinase gene terminater), mouse Skp2 genomic DNA
Research application
提供条件条件を付加する。利用者は事前に寄託者の提供承諾書を得る。
共同研究
Depositor中山　敬一（国立大学法人九州大学）
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)
Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

No Data