Strain Data Sheet

RBRC00442

Strain Information

Image
BRC No.RBRC00442
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Nbl1<tm1Saki>/SakiRbrc
Former Common nameDAN Knockout mice
H-2 Haplotype
ES Cell lineR1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Background strainC57BL/6NCrlCrlj
Appearanceblack
Strain development
Strain description
Colony maintenance
References
Cloning of mouse DAN cDNA and its down-regulation in transformed cells.
T Ozaki, J Ma, K Takenaga, S Sakiyama
Jpn. J. Cancer Res., 87, 58-61 (1996). 8609050

Tumor-Suppressing Viruses, Genes and Drugs Innovative Cancer Therapy Approaches, 221-231 (2002).

Reduced inflammatory pain in mice deficient in the differential screening-selected gene aberrative in neuroblastoma.
S Ohtori, E Isogai, F Hasue, T Ozaki, Y Nakamura, A Nakagawara, H Koseki, S Yuasa, E Hanaoka, J Shinbo, T Yamamoto, H Chiba, M Yamazaki, H Moriya, S Sakiyama
Mol. Cell Neurosci., 25(3):504-14 (2004). 15033178

Health Report

Examination Date / Room / Rack2025/11/17Room:3-CRack:I囮検査
2025/09/08Room:3-CRack:I囮検査
2025/06/30Room:3-CRack:I囮検査
2025/04/21Room:3-CRack:I囮検査
2025/01/27Room:3-CRack:I追加検査
2025/01/20Room:3-CRack:I囮検査
2024/10/21Room:3-CRack:I囮検査

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Nbl1
MGI:104591		NBL1, DAN family BMP antagonist4Nbl1<tm1Saki>
MGI:3042574		targeted mutation 1, S Sakiyama
neo neomycin resistance gene (E. coli)4 herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • abnormal pain threshold (MP:0001970)
    • Detailed phenotype data

    Ordering Information

    供与核酸herpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, mouse Nbl1 genomic DNA
    Research application
    提供条件条件を付加しない。
    Depositor崎山　樹（千葉県がんセンター研究所）
    Strain Status凍結胚のアイコン凍結胚
    凍結精子のアイコン凍結精子
    Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
    凍結精子を1ヶ月以内に提供可能
    凍結胚を1ヶ月以内に提供可能
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data