Strain Information | |
---|---|
Image | |
BRC No. | RBRC00442 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129-Nbl1<tm1Saki>/SakiRbrc |
Former Common name | DAN Knockout mice |
H-2 Haplotype | |
ES Cell line | R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>] |
Background strain | C57BL/6NCrlCrlj |
Appearance | black |
Strain development | |
Strain description | |
Colony maintenance | |
References | Cloning of mouse DAN cDNA and its down-regulation in transformed cells. Ozaki T, Ma J, Takenaga K, Sakiyama S Jpn. J. Cancer Res., 87, 58-61 (1996). 8609050Reduced inflammatory pain in mice deficient in the differential screening-selected gene aberrative in neuroblastoma. Ohtori S, Isogai E, Hasue F, Ozaki T, Nakamura Y, Nakagawara A, Koseki H, Yuasa S, Hanaoka E, Shinbo J, Yamamoto T, Chiba H, Yamazaki M, Moriya H, Sakiyama S Mol. Cell Neurosci., 25(3):504-14 (2004). 15033178Tumor-Suppressing Viruses, Genes and Drugs Innovative Cancer Therapy Approaches, 221-231 (2002). |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |||||||
---|---|---|---|---|---|---|---|
Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Nbl1 | NBL1, DAN family BMP antagonist | 4 | Nbl1 | targeted mutation 1, S Sakiyama | |||
neo | neomycin resistance gene (E. coli) | 4 | herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Phenotype | |
---|---|
Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
---|---|
Donor DNA | herpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, mouse Nbl1 genomic DNA |
Research application | |
Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
Depositor | Shigeru Sakiyama (Chiba Cancer Center) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
---|
No Data |