Strain Data Sheet

RBRC00431

Strain Information

Image
BRC No.RBRC00431
TypeWild-derived Inbred
SpeciesMus musculus molossinus
Strain nameMol-Mae/Stm
Former Common nameM. m. molossinus Mae-1, Mol-Mae/Stm
H-2 Haplotype
ES Cell line
Background strainMAE [Mus musculus molossinus]
Appearance
Strain developmentDeveloped by Yoshibumi Matsushima, Saitama Cancer Center.
Strain descriptionWild-derived strain of Mus musculus molossinus, collected at Maesawa-cho,Tanzawa-gun, Iwate-prefecture, Japan in 1988.
Colony maintenance
References
Gene responsible for deficient activity of the beta subunit of C8, the eighth component of complement, is located on mouse chromosome 4.
Tanaka S, Suzuki T, Sakaizumi M, Harada Y, Matsushima Y, Miyashita N, Fukumori Y, Inai S, Moriwaki K, Yonekawa H
Immunogenetics, 33, 18-23 (1991). 1995474

Japanese wild mice: a rich resource for new disease models.
Matsushima Y
Exp. Anim., 61, 25-33 (2012). 22293669

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
C8bcomplement component 8, beta polypeptide4C8b<0>
  • type II complement component 8 deficiency(MedGEN)
  • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorYoshibumi Matsushima (Saitama Cancer Center)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Click Here for Mouse genomic DNA (RIKEN DNA Bank)

    BRC mice in Publications

    Takada T, Ebata T, Noguchi H, Keane TM, Adams DJ, Narita T, Shin-I T, Fujisawa H, Toyoda A, Abe K, Obata Y, Sakaki Y, Moriwaki K, Fujiyama A, Kohara Y, Shiroishi T.
    The ancestor of extant Japanese fancy mice contributed to the mosaic genomes of classical inbred strains.
    Genome Res 23(8) 1329-38(2013) 23604024
    Bamunusinghe D, Naghashfar Z, Buckler-White A, Plishka R, Baliji S, Liu Q, Kassner J, Oler AJ, Hartley J, Kozak CA.
    Sequence Diversity, Intersubgroup Relationships, and Origins of the Mouse Leukemia Gammaretroviruses of Laboratory and Wild Mice.
    J Virol 90(8) 4186-98(2016) 26865715
    Bamunusinghe D, Liu Q, Lu X, Oler A, Kozak CA.
    Endogenous gammaretrovirus acquisition in Mus musculus subspecies carrying functional variants of the XPR1 virus receptor.
    J Virol 87(17) 9845-55(2013) 23824809
    Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.
    Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus.
    PLoS One 9(12) e114305(2014) 25470728