Strain Data Sheet

RBRC00357

Strain Information

Image
BRC No.RBRC00357
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC.Cg-Tnc<tm1Sia> Foxn1<nu>/Rbrc
Former Common nameBALB/cA-Tnc<tm1Sia>-nude; BALB/cA-TgH(Tnc)-Foxn1nu
H-2 Haplotype
ES Cell line
Background strainBALB/cA
Appearance
Strain developmentDeveloped by Dr. M. Kusakabe, Tsukuba Life Science Center, Institute of Physical and Chemical Research (RIKEN).
Strain descriptionC.Cg-Tnc<tm1Sia> Foxn1<nu>. Mice lacking tenascin C gene with a nude mutation. This strain is useful for studying the function of tenascin C in tumor proliferation and metastasis, neoangiogenesis, interoganizartional interation, and transplantation of human tumor.
Colony maintenance
References22nd Congress of the International Association for Breast Cancer Research Athens, Greece 25-28 September, pp 197-201 (1998). 9863494
Genes Dev., 6, 1821-1831 (1992). 1383086
Biochem. Biophys. Res. Commun., 231, 356-359 (1997). 9070278
Gene, 104, 177-185 (1991). 1717349
Biochem. Biophys. Res. Commun., 290, 1220-1227 (2002). 11811993
J. Comp. Neurol., 430, 485-500 (2001). 11169482
Biochem. Biophys. Res. Commun., 221, 151-156 (1996). 8660327
Am. J. Pathol., 152, 1237-1245 (1998). 9588892
J. Invest. Dermatol., 111, 930-935 (1998). 9856798
Invest. Ophthalmol. Visual. Sci., 40, 1071-1080 (1999). 10235540
Exp. Mol. Pathol., 72, 186-195 (2002). 12009782
J. Neurosci., 15, 1971-1983 (1995). 7534342
乳癌基礎研究, 8, 26-31 (1999).
乳癌基礎研究, 5, 41-45 (1996).
炎症, 15(5), 377-381 (1996).

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Foxn1forkhead box N111Foxn1<nu>nudeD11Bhm185e, Hfh11, whn

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Tnctenascin C4Tnc<tm1Sia>targeted mutation 1, Shinichi AizawaTnc; tenascin C, Hxb, Ten, TN-C, AI528729

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
lacZbeta-galactosidase (E. coli)4

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)4neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

Donor DNAE. coli lacZ, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse tenascin genomic DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Am. J. Pathol., 152, 1237-1245 (1998). J. Invest. Dermatol., 111, 930-935 (1998). Invest. Ophthalmol. Visual. Sci., 40, 1071-1080 (1999).
DepositorRIKEN BRC (RIKEN BRC)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data