BRC No.RBRC00234
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.Cg-Chrne<tm1Mtak>/Rbrc
Former Common nameC57BL/6-TgH(AchR-epsilon)
H-2 Haplotype
ES Cell lineRW4 [129X1/SvJ]
Background strainC57BL/6JJcl
Strain development
Strain description
Colony maintenance
ReferencesProc. Natl. Acad. Sci. USA, 95, 13413-13418 (1998). 9811814
FEBS Lett., 223, 104-112 (1987). 3666131
EMBO Rep., 3, 674-681 (2002). 12101101
Development, 124, 5075-5086 (1997). 9362465
Proc. Natl. Acad. Sci. USA, 93, 13286-13291 (1996). 8917583

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Chrnecholinergic receptor, nicotinic, epsilon polypeptide11Chrne<tm1Mtak>targeted mutation 1, Masazumi Takahashi

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)11herpes simplex virus thymidine kinase promoter (HSV tk promoter)


Donor DNAmouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse muscle type nicotinic acetylcholine receptor epsilon subunit genomic DNA
Research application
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorMasazumi Takahashi (Centre National de Genotypage)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data