Strain Data Sheet


Strain Information

BRC No.RBRC00213
TypeWild-derived Inbred
SpeciesMus musculus musculus
Strain namePWK
Former Common name
H-2 Haplotype
ES Cell line
Background strainPWK [Mus musculus musculus]
Appearanceagouti [A/A]
Strain developmentDeposited by Rosemary Elliott, Roswell Park Cancer Institute.
Strain descriptionPWK is descended by sib mating from a single pair of mice of the subspecies Mus musculus musculus caught in 1974 in Lhotka, Czech Republic. F1 hybrid males between C57BL/6 and PWK were found to be sterile.
Colony maintenanceSibling x Sibling.
ReferencesDev. Biol., 198, 266-276 (1998). 9659932
Proc. Natl. Acad. Sci. USA, 89, 3232-3235 (1992). 1314381
Mamm. Genome, 13, 293-298 (2002). 12115031
Genetics, 162, 831-840 (2002). 12399393
Cell, 63, 717-728 (1990). 2225073
Blood, 83, 3225-3231 (1994). 8193357

Health Report

Examination Date / Room / Rack2024/02/26Room:4-CRack:B


Gene info

Ordering Information

Donor DNA
Research applicationCell Biology Research
Developmental Biology Research
Genetics Research
Reproductive Biology Research
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorRoswell Park Cancer Inst. (Roswell Park Cancer Inst.)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Live mouse (3 to 6 months)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Click Here for Mouse genomic DNA (RIKEN DNA Bank)

BRC mice in Publications

Fujiwara K, Igarashi J, Irahara N, Kimura M, Nagase H.
New chemically induced skin tumour susceptibility loci identified in a mouse backcross between FVB and dominant resistant PWK.
BMC Genet 8 39(2007) 17598916

Horii T, Yanagisawa E, Kimura M, Morita S, Hatada I.
Epigenetic differences between embryonic stem cells generated from blastocysts developed in vitro and in vivo.
Cell Reprogram 12(5) 551-63(2010) 20818993

Saito A, Tahara R, Hirose M, Kadota M, Hasegawa A, Kondo S, Kato H, Amano T, Yoshiki A, Ogura A, Kiyosawa H.
Inter-subspecies mouse F1 hybrid embryonic stem cell lines newly established for studies of allelic imbalance in gene expression.
Exp Anim (2024) 38447983

Kayashima T, Yamasaki K, Joh K, Yamada T, Ohta T, Yoshiura K, Matsumoto N, Nakane Y, Mukai T, Niikawa N, Kishino T.
Atp10a, the mouse ortholog of the human imprinted ATP10A gene, escapes genomic imprinting.
Genomics 81(6) 644-7(2003) 12782135

Yamasaki Y, Kayashima T, Soejima H, Kinoshita A, Yoshiura K, Matsumoto N, Ohta T, Urano T, Masuzaki H, Ishimaru T, Mukai T, Niikawa N, Kishino T.
Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air.
Hum Mol Genet 14(17) 2511-20(2005) 16037066

Bamunusinghe D, Naghashfar Z, Buckler-White A, Plishka R, Baliji S, Liu Q, Kassner J, Oler AJ, Hartley J, Kozak CA.
Sequence Diversity, Intersubgroup Relationships, and Origins of the Mouse Leukemia Gammaretroviruses of Laboratory and Wild Mice.
J Virol 90(8) 4186-98(2016) 26865715

Komatsu S, Kiyosawa H, Yoshiki A, Okazaki Y, Yoshino M, Tomaru Y, Watanabe S, Muramatsu M, Kusakabe M, Hayashizaki Y.
Identification of seven loci for static glucokinesis and dynamic glucokinesis in mice.
Mamm Genome 13(6) 293-8(2002) 12115031

Hayashida K, Kohno S.
Hybrid male sterility is caused by mitochondrial DNA deletion.
Mol Biol Rep 36(6) 1365-9(2009) 18649010

Yamasaki-Ishizaki Y, Kayashima T, Mapendano CK, Soejima H, Ohta T, Masuzaki H, Kinoshita A, Urano T, Yoshiura K, Matsumoto N, Ishimaru T, Mukai T, Niikawa N, Kishino T.
Role of DNA methylation and histone H3 lysine 27 methylation in tissue-specific imprinting of mouse Grb10.
Mol Cell Biol 27(2) 732-42(2007) 17101788

Wang Y, Joh K, Masuko S, Yatsuki H, Soejima H, Nabetani A, Beechey CV, Okinami S, Mukai T.
The mouse Murr1 gene is imprinted in the adult brain, presumably due to transcriptional interference by the antisense-oriented U2af1-rs1 gene.
Mol Cell Biol 24(1) 270-9(2004) 14673161

Fujiwara K, Inagaki Y, Soma M, Ozaki T, Nagase H.
Mapping of new skin tumor susceptibility loci by a phenotype-driven congenic approach.
Oncol Lett 16(5) 6670-6676(2018) 30405807

Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.
Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus.
PLoS One 9(12) e114305(2014) 25470728

Morita S, Horii T, Kimura M, Arai Y, Kamei Y, Ogawa Y, Hatada I.
Paternal allele influences high fat diet-induced obesity.
PLoS One 9(1) e85477(2014) 24416415

Morita S, Nakabayashi K, Kawai T, Hayashi K, Horii T, Kimura M, Kamei Y, Ogawa Y, Hata K, Hatada I.
Gene expression profiling of white adipose tissue reveals paternal transmission of proneness to obesity.
Sci Rep 6 21693(2016) 26868178