Strain Data Sheet


Strain Information

BRC No.RBRC00208
TypeWild-derived strain, partially inbred
SpeciesMus spretus
Strain nameM. spretus
Former Common nameM. spretus
H-2 Haplotype
ES Cell line
Background strainSPR2 [Mus spretus]
Appearancewhite-bellied agouti [Aw/Aw , B/B, C/C]
Strain developmentDeposited by Rosemary Elliott, Roswell Park Cancer Institute.
Strain descriptionM. spretus, SPR2 inbred strain, derived from Mus spretus wild mice trapped in Spain and maintained by Roswell Park Cancer Institute as random stock. Mice were introduced to the RIKEN Tsukuba Institute in 1998 from Dr. Verene Chapman. Among them the inbred line has been created. This strain has been reported to be resistant to the development of skin cancer. M.spretus produces sterile F1 males with laboratory strains.
Colony maintenanceSibling x Sibling.
ReferencesBiochem. Genet., 16(3-4):213-225 (1978). 678291

Health Report

Examination Date / Room / Rack2024/02/26Room:4-CRack:E


Gene info

Ordering Information

Donor DNA
Research applicationGenetics Research
Reproductive Biology Research
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorRoswell Park Cancer Inst. (Roswell Park Cancer Inst.)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Click Here for Mouse genomic DNA (RIKEN DNA Bank)

BRC mice in Publications

Kawakami M, Yamamura K.
Cranial bone morphometric study among mouse strains.
BMC Evol Biol 8 73(2008) 18307817

Hasegawa A, Mochida K, Matoba S, Inoue K, Hama D, Kadota M, Hiraiwa N, Yoshiki A, Ogura A.
Development of assisted reproductive technologies for Mus spretus†.
Biol Reprod 104(1) 234-243(2021) 32990726

Kono H, Tamura M, Osada N, Suzuki H, Abe K, Moriwaki K, Ohta K, Shiroishi T.
Prdm9 polymorphism unveils mouse evolutionary tracks.
DNA Res 21(3) 315-26(2014) 24449848

Oka A, Mita A, Takada Y, Koseki H, Shiroishi T.
Reproductive isolation in hybrid mice due to spermatogenesis defects at three meiotic stages.
Genetics 186(1) 339-51(2010) 20610405

Kaneko S, Aki I, Tsuda K, Mekada K, Moriwaki K, Takahata N, Satta Y.
Origin and evolution of processed pseudogenes that stabilize functional Makorin1 mRNAs in mice, primates and other mammals.
Genetics 172(4) 2421-9(2006) 16415359

Johnsen JM, Levy GG, Westrick RJ, Tucker PK, Ginsburg D.
The endothelial-specific regulatory mutation, Mvwf1, is a common mouse founder allele.
Mamm Genome 19(1) 32-40(2008) 18188647

Hirotsune S, Yoshida N, Chen A, Garrett L, Sugiyama F, Takahashi S, Yagami K, Wynshaw-Boris A, Yoshiki A.
An expressed pseudogene regulates the messenger-RNA stability of its homologous coding gene.
Nature 423(6935) 91-6(2003) 12721631

Aizawa S, Nishimura K, Mondejar GS, Kumar A, Bui PL, Tran YTH, Kuno A, Muratani M, Kobayashi S, Nabekura T, Shibuya A, Sugihara E, Sato TA, Fukuda A, Hayashi Y, Hisatake K.
Early reactivation of clustered genes on the inactive X chromosome during somatic cell reprogramming.
Stem Cell Reports 17(1) 53-67(2022) 34919813