Strain Data Sheet

RBRC00208

Strain Information

Image
BRC No.RBRC00208
TypeWild-derived strain, partially inbred
SpeciesMus spretus
Strain nameM. spretus
Former Common nameM. spretus
H-2 Haplotype
ES Cell line
Background strainSPR2 [Mus spretus]
Appearancewhite-bellied agouti [Aw/Aw , B/B, C/C]
Strain developmentDeposited by Rosemary Elliott, Roswell Park Cancer Institute.
Strain descriptionM. spretus, SPR2 inbred strain, derived from Mus spretus wild mice trapped in Spain and maintained by Roswell Park Cancer Institute as random stock. Mice were introduced to the RIKEN Tsukuba Institute in 1998 from Dr. Verene Chapman. Among them the inbred line has been created. This strain has been reported to be resistant to the development of skin cancer. M.spretus produces sterile F1 males with laboratory strains.
Colony maintenanceSibling x Sibling.
References
Evidence for the presence of two sympatric species of mice (genus Mus L.) in southern France based on biochemical genetics.
Britton J, Thaler L
Biochem. Genet., 16(3-4):213-225 (1978). 678291

Health Report

Examination Date / Room / Rack2024/08/26Room:4-CRack:E
2024/05/27Room:4-CRack:E
2024/02/26Room:4-CRack:E
2023/11/27Room:4-CRack:E
2023/08/28Room:4-CRack:E
2023/05/29Room:4-CRack:E
2023/02/27Room:4-CRack:E
2022/11/29Room:4-CRack:E

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationGenetics Research
    Reproductive Biology Research
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorRoswell Park Cancer Inst. (Roswell Park Cancer Inst.)
    Strain Statusan icon for Live miceLive mice
    an icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityCryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Live mouse (1 to 3 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Click Here for Mouse genomic DNA (RIKEN DNA Bank)

    BRC mice in Publications

    Kawakami M, Yamamura K.
    Cranial bone morphometric study among mouse strains.
    BMC Evol Biol 8 73(2008) 18307817
    Hasegawa A, Mochida K, Matoba S, Inoue K, Hama D, Kadota M, Hiraiwa N, Yoshiki A, Ogura A.
    Development of assisted reproductive technologies for Mus spretus†.
    Biol Reprod 104(1) 234-243(2021) 32990726
    Kono H, Tamura M, Osada N, Suzuki H, Abe K, Moriwaki K, Ohta K, Shiroishi T.
    Prdm9 polymorphism unveils mouse evolutionary tracks.
    DNA Res 21(3) 315-26(2014) 24449848
    Oka A, Mita A, Takada Y, Koseki H, Shiroishi T.
    Reproductive isolation in hybrid mice due to spermatogenesis defects at three meiotic stages.
    Genetics 186(1) 339-51(2010) 20610405
    Kaneko S, Aki I, Tsuda K, Mekada K, Moriwaki K, Takahata N, Satta Y.
    Origin and evolution of processed pseudogenes that stabilize functional Makorin1 mRNAs in mice, primates and other mammals.
    Genetics 172(4) 2421-9(2006) 16415359
    Johnsen JM, Levy GG, Westrick RJ, Tucker PK, Ginsburg D.
    The endothelial-specific regulatory mutation, Mvwf1, is a common mouse founder allele.
    Mamm Genome 19(1) 32-40(2008) 18188647
    Hirotsune S, Yoshida N, Chen A, Garrett L, Sugiyama F, Takahashi S, Yagami K, Wynshaw-Boris A, Yoshiki A.
    An expressed pseudogene regulates the messenger-RNA stability of its homologous coding gene.
    Nature 423(6935) 91-6(2003) 12721631
    Aizawa S, Nishimura K, Mondejar GS, Kumar A, Bui PL, Tran YTH, Kuno A, Muratani M, Kobayashi S, Nabekura T, Shibuya A, Sugihara E, Sato TA, Fukuda A, Hayashi Y, Hisatake K.
    Early reactivation of clustered genes on the inactive X chromosome during somatic cell reprogramming.
    Stem Cell Reports 17(1) 53-67(2022) 34919813