Strain Data Sheet
RBRC00191
Strain Information | |
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| Image |  |
| BRC No. | RBRC00191 |
| Type | Inbred |
| Species | Mus musculus |
| Strain name | GRS/A |
| Former Common name | grs; |
| H-2 Haplotype | ? |
| ES Cell line | |
| Background strain | GRS/A |
| Appearance | albino [a/a Tyrc/Tyrc] |
| Strain development | オランダで育成されたアルビノ近交系。乳癌を高発する。妊娠を繰り返す事により,ホルモン依存性に乳癌を発症する。乳癌モデルとして有用。寄託者：高橋利忠（愛知県がんセンター） 研究分野： Cancer Generation:+F40+F27兄妹交配による維持。初産仔マウスの生育は悪い。乳腺の発達不良によると言われている。雌：雄１：１でも維持可能だが、仔の発育の為、雌を複数同居させることが望ましい。 |
| Strain description | Breeding females have a high incidence of mammary tumours which are highly hormone-responsive. |
| Colony maintenance | |
| References | J. Natl. Cancer Inst., 56, 27-32 (1976). Int. J. Cancer, 19, 383-390 (1977). Mammary tumors in the mouse. (1981). Characterization and chromosomal distribution of endogenous mouse mammary tumor viruses of European mouse strains STS/A and GR/A. R Michalides, R Verstraeten, F W Shen, J Hilgers Virology, 142, 278-290 (1985). 2997987Tcrb-V3+ T-cell deletion and a new mouse mammary tumor provirus, Mtv-44. S Fairchild, O A Rosenwasser, P J Dyson, K Tomonari Immunogenetics, 36, 189-194 (1992). 1319398 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
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| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Mtv2 MGI:97188 | mammary tumor virus locus 2 | 18 | Mtv2<a> MGI:3579297 | present | |||
Phenotype | |
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| Phenotype annotation from literatures by Mammalian phenotype ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| 供与核酸 | |
| Research application | Cancer Research Immunology and Inflammation Research Virology Research |
| 提供条件 | 条件を付加しない。 |
| Depositor | 高橋 利忠（愛知県がんセンター） |
| Strain Status |  凍結胚 |
| Strain Availability | 凍結胚より作出したマウスを2~4ヶ月以内に提供可能 |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |