Strain Data Sheet

RBRC00191

Strain Information

Image
BRC No.RBRC00191
TypeInbred
SpeciesMus musculus
Strain nameGRS/A
Former Common namegrs;
H-2 Haplotype?
ES Cell line
Background strainGRS/A
Appearancealbino [a/a Tyrc/Tyrc]
Strain developmentFormerly called GR/A. Muhlbock 1965 from outbred mice obtained fromGrumbach in Zurich. Imported from Amsterdam, Netherland to Dr. Sakakura T, Aichi Cancer Cetnter Research Institute.
Strain descriptionBreeding females have a high incidence of mammary tumours which are highly hormone-responsive.
Colony maintenance
References
Genetic analysis of mammary tumor induction and expression of mammary tumor virus antigen in hormone-treated ovariectomized GR mice.
van Nie R, Hilgers J
J. Natl. Cancer Inst., 56, 27-32 (1976). 176379

Genetic transmission of mammary tumour virus by GR mice.
Van Nie R, Verstraeten A A, De Moes J
Int. J. Cancer, 19, 383-390 (1977). 191409

Mammary tumors in the mouse. (1981).

Characterization and chromosomal distribution of endogenous mouse mammary tumor viruses of European mouse strains STS/A and GR/A.
Michalides R, Verstraeten R, Shen F W, Hilgers J
Virology, 142, 278-290 (1985). 2997987

Tcrb-V3+ T-cell deletion and a new mouse mammary tumor provirus, Mtv-44.
Fairchild S, Rosenwasser O A, Dyson P J, Tomonari K
Immunogenetics, 36, 189-194 (1992). 1319398

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Mtv2
MGI:97188		mammary tumor virus locus 218Mtv2<a>
MGI:3579297		present

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal mammary gland development(MP:0000628)

  • increased mammary adenocarcinoma incidence(MP:0001883)

  • mammary gland alveolar hyperplasia(MP:0001884)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationCancer Research
    Immunology and Inflammation Research
    Virology Research
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorToshitada Takahashi (Aichi Cancer Center)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data