Strain Information | |
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Image | |
BRC No. | RBRC00165 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129S4-Zic2<tm1Jaru>/JaruRbrc |
Former Common name | C57BL/6N-Kd(Zic2), Zic2 Knockdown mouse |
H-2 Haplotype | |
ES Cell line | J1 [129S4/SvJae] |
Background strain | C57BL/6N |
Appearance | black |
Strain development | |
Strain description | |
Colony maintenance | |
References | J. Neurosci., 22, 218-225 (2002). 11756505 Proc. Natl. Acad. Sci. USA, 97, 1618-1623 (2000). 10677508 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)14neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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供与核酸 | mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse Zic2 (Zic finger protein of the cerebellum 2) genomic DNA |
Research application | Neurobiology Research |
提供条件 | 条件を付加する。利用者は事前に寄託者の提供承諾書を得る。 研究成果の公表にあたって寄託者の指定する文献を引用する。Proc. Natl. Acad. Sci. USA, 97, 1618-1623 (2000). |
Depositor | 有賀 純(理化学研究所脳科学総合研究センター) |
Strain Status | 凍結胚 凍結精子 |
Strain Availability | 凍結胚より作出したマウスを2~4ヶ月以内に提供可能 凍結精子を1ヶ月以内に提供可能 凍結胚を1ヶ月以内に提供可能 |
Additional Info. | Necessary documents for ordering:
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BRC mice in Publications |
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García-Frigola C, Carreres MI, Vegar C, Mason C, Herrera E. Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and -independent mechanisms. Development 135(10) 1833-41(2008) 18417618 García-Frigola C, Herrera E. Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets. EMBO J 29(18) 3170-83(2010) 20676059 Sánchez-Arrones L, Nieto-Lopez F, Sánchez-Camacho C, Carreres MI, Herrera E, Okada A, Bovolenta P. Shh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina. J Neurosci 33(20) 8596-607(2013) 23678105 |