Strain Data Sheet

RBRC00164

Strain Information

Image
BRC No.RBRC00164
TypeSpontaneous Mutation Congenic
SpeciesMus musculus
Strain nameB6.C3-Kit<W-f>/Rbrc
Former Common nameC57BL/6-W<f>/+
H-2 Haplotype
ES Cell line
Background strain
AppearanceBlack with extensive depigmented areas lacking a defined pattern [a/a B/B C/C W/W]
Strain developmentSpontaneous mutation originally arosed in C3H/HePas. The B6.C3-Kit<W-f> congenic strain was generated by backcrossed to C57BL/6 by Dr. Y. Kitamura, then deposited to the RIKEN BRC.
Strain descriptionB6.C3-Kit<W-f>/Rbrc. Fertile dominant spotting. The original Kit<W-f> mutation arose spontaneously in the C3H/HePas strain. The B6.C3-Kit<W-f> congenic strain was generated by backcrossed to C57BL/6 by Dr. Y. Kitamura. Homozygous mice for Kit<W-f> are black with white sash. Typical dilution of pigmented areas not observed. The c-Kit cDNA from Kit<W-f>/ Kit<W-f> mice showed an AT to TA transversion at nucleotide 2474 that resulted in the change from Arg to Trp at position 816.
Colony maintenanceSibling Mating (Homozygote x Homozygote)
References

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Kitkit oncogene5Kit<W-f>fertile dominant spotting

Ordering Information

供与核酸
Research application
提供条件条件を付加しない。
Depositor北村 幸彦(大阪大学)
Strain Status凍結胚のアイコン凍結胚
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

BRC mice in Publications

No Data