Strain Information | |
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Image | |
BRC No. | RBRC00164 |
Type | Spontaneous Mutation Congenic |
Species | Mus musculus |
Strain name | B6.C3-Kit<W-f>/Rbrc |
Former Common name | C57BL/6-W<f>/+ |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | Black with extensive depigmented areas lacking a defined pattern [a/a B/B C/C W/W] |
Strain development | Spontaneous mutation originally arosed in C3H/HePas. The B6.C3-Kit<W-f> congenic strain was generated by backcrossed to C57BL/6 by Dr. Y. Kitamura, then deposited to the RIKEN BRC. |
Strain description | B6.C3-Kit<W-f>/Rbrc. Fertile dominant spotting. The original Kit<W-f> mutation arose spontaneously in the C3H/HePas strain. The B6.C3-Kit<W-f> congenic strain was generated by backcrossed to C57BL/6 by Dr. Y. Kitamura. Homozygous mice for Kit<W-f> are black with white sash. Typical dilution of pigmented areas not observed. The c-Kit cDNA from Kit<W-f>/ Kit<W-f> mice showed an AT to TA transversion at nucleotide 2474 that resulted in the change from Arg to Trp at position 816. |
Colony maintenance | Sibling Mating (Homozygote x Homozygote) |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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供与核酸 | |
Research application | |
提供条件 | 条件を付加しない。 |
Depositor | 北村 幸彦(大阪大学) |
Strain Status | 凍結胚 |
Strain Availability | 凍結胚より作出したマウスを2~4ヶ月以内に提供可能 凍結胚を1ヶ月以内に提供可能 |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |