Strain Data Sheet

RBRC00164

Strain Information

Image
BRC No.RBRC00164
TypeSpontaneous Mutation Congenic
SpeciesMus musculus
Strain nameB6.C3-Kit<W-f>/Rbrc
Former Common nameC57BL/6-W<f>/+
H-2 Haplotype
ES Cell line
Background strain
AppearanceBlack with extensive depigmented areas lacking a defined pattern [a/a B/B C/C W/W]
Strain developmentSpontaneous mutation originally arosed in C3H/HePas. The B6.C3-Kit<W-f> congenic strain was generated by backcrossed to C57BL/6 by Dr. Y. Kitamura, then deposited to the RIKEN BRC.
Strain descriptionB6.C3-Kit<W-f>/Rbrc. Fertile dominant spotting. The original Kit<W-f> mutation arose spontaneously in the C3H/HePas strain. The B6.C3-Kit<W-f> congenic strain was generated by backcrossed to C57BL/6 by Dr. Y. Kitamura. Homozygous mice for Kit<W-f> are black with white sash. Typical dilution of pigmented areas not observed. The c-Kit cDNA from Kit<W-f>/ Kit<W-f> mice showed an AT to TA transversion at nucleotide 2474 that resulted in the change from Arg to Trp at position 816.
Colony maintenanceSibling Mating (Homozygote x Homozygote)
References

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Kitkit oncogene5Kit<W-f>fertile dominant spotting

Ordering Information

Donor DNA
Research application
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorYukihiko Kitamura (Osaka University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

BRC mice in Publications

No Data