Strain Data Sheet

RBRC00152

Strain Information

Image
BRC No.RBRC00152
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.Cg-Ryr3<tm1Jms>/Rbrc
Former Common nameC57BL/6-TgH(RyR3)
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strainC57BL/6
Appearanceblack [a/a]
Strain development
Strain description
Colony maintenance
References
Facilitation of NMDAR-independent LTP and spatial learning in mutant mice lacking ryanodine receptor type 3.
Futatsugi A, Kato K, Ogura H, Li S T, Nagata E, Kuwajima G, Tanaka K, Itohara S, Mikoshiba K
Neuron, 24, 701-13 (1999). 10595520

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Ryr3
MGI:99684		ryanodine receptor 32Ryr3<tm1Jms>
MGI:3575753		targeted mutation 1, Institute of Medical Science, Japan
neo neomycin resistance gene (E. coli)2 mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • abnormal spatial learning (MP:0001463)

  • absent long-term depression (MP:0001899)

  • enhanced long-term potentiation (MP:0003008)
    • Detailed phenotype data

    Ordering Information

    供与核酸mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse Ryanodine receptor type3 (RyR3) genomic DNA
    Research applicationCell Biology Research
    Neurobiology Research
    提供条件利用者は事前に寄託者の提供承諾書を得る。研究成果の公表にあたって寄託者の指定する文献を引用する。研究成果の公表にあたって謝辞の表明を必要とする。公表を前提とした学術研究に限る。
    Depositor御子柴　克彦（理化学研究所脳科学総合研究センター）
    Strain Status凍結胚のアイコン凍結胚
    凍結精子のアイコン凍結精子
    Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
    凍結精子を1ヶ月以内に提供可能
    凍結胚を1ヶ月以内に提供可能
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data