Strain Data Sheet

Todo K, Hikida M.
T cell-mediated immune surveillance suppresses an endogenous retrovirus Emv10 in C57BL/6-Ly5.1 mice.
Biochem Biophys Res Commun 815 153687(2026) 41905167

Forgioni A, Watanabe M, Goto R, Harada T, Ota T, Shimamura T, Taketomi A.
Anti-Inflammatory Effects of Ex Vivo-Generated Donor Antigen-Specific Immunomodulatory Cells on Pancreatic Islet Transplantation.
Cell Transplant 34 9636897251317887(2025) 39981681

Srirat T, Hayakawa T, Mise-Omata S, Nakagawara K, Ando M, Shichino S, Ito M, Yoshimura A.
NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment.
Cell Rep 43(3) 113898(2024) 38451819

Yanagi M, Ikegami I, Kamekura R, Sato T, Sato T, Kamiya S, Murayama K, Jitsukawa S, Ito F, Yorozu A, Kihara M, Abe T, Takaki H, Kawata K, Shigehara K, Miyajima S, Nishikiori H, Sato A, Tohse N, Takano KI, Chiba H, Ichimiya S.
Bob1 maintains T follicular helper cells for long-term humoral immunity.
Commun Biol 7(1) 185(2024) 38360857

Furuya H, Toda Y, Iwata A, Kanai M, Kato K, Kumagai T, Kageyama T, Tanaka S, Fujimura L, Sakamoto A, Hatano M, Suto A, Suzuki K, Nakajima H.
Stage-specific GATA3 induction promotes ILC2 development after lineage commitment.
Nat Commun 15(1) 5610(2024) 38969652

Tokifuji Y, Hayabuchi H, Sasaki T, Hara-Chikuma M, Hirota K, Takahashi H, Amagai M, Yoshimura A, Chikuma S.
Targeting abatacept-resistant T-helper-17 cells by aldehyde dehydrogenase inhibition.
iScience 27(1) 108646(2024) 38226171

Mise-Omata S, Ando M, Srirat T, Nakagawara K, Hayakawa T, Iizuka-Koga M, Nishimasu H, Nureki O, Ito M, Yoshimura A.
SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine.
Cell Rep 112940(2023) 37582370

Sano T, Ueda K, Minakawa K, Mori T, Hashimoto Y, Koseki H, Takeishi Y, Ikeda K, Ikezoe T.
Impaired Repopulating Ability of Uhrf2-/- Hematopoietic Progenitor Cells in Mice.
Genes (Basel) 14(8) (2023) 37628583

Sumii Y, Kondo T, Ikegawa S, Fukumi T, Iwamoto M, Nishimura MF, Sugiura H, Sando Y, Nakamura M, Meguri Y, Matsushita T, Tanimine N, Kimura M, Asada N, Ennishi D, Maeda Y, Matsuoka KI.
Hematopoietic stem cell-derived Tregs are essential for maintaining favorable B cell lymphopoiesis following posttransplant cyclophosphamide.
JCI Insight 8(8) (2023) 37092551

Suga K, Suto A, Tanaka S, Sugawara Y, Kageyama T, Ishikawa J, Sanayama Y, Ikeda K, Furuta S, Kagami SI, Iwata A, Hirose K, Suzuki K, Ohara O, Nakajima H.
TAp63, a methotrexate target in CD4+ T cells, suppresses Foxp3 expression and exacerbates autoimmune arthritis.
JCI Insight 8(10) (2023) 37212280

Lu L, Kuroishi T, Tanaka Y, Furukawa M, Nochi T, Sugawara S.
Differential expression of CD11c defines two types of tissue-resident macrophages with different origins in steady-state salivary glands.
Sci Rep 12(1) 931(2022) 35042931

Kondo T, Ikegawa S, Fukumi T, Sumii Y, Sugiura H, Sando Y, Nakamura M, Meguri Y, Iwamoto M, Maeda Y, Matsuoka KI.
Pretransplant Short-Term Exposure of Donor Graft Cells to ITK Selective Inhibitor Ameliorates Acute Graft-versus-Host Disease by Inhibiting Effector T Cell Differentiation while Sparing Regulatory T Cells.
Immunohorizons 5(6) 424-437(2021) 34112701

Hosaka N, Kanda S, Shimono T, Nishiyama T.
Induction of γδT cells from HSC-enriched BMCs co-cultured with iPSC-derived thymic epithelial cells.
J Cell Mol Med 25(22) 10604-10613(2021) 34687276

Nakamura M, Meguri Y, Ikegawa S, Kondo T, Sumii Y, Fukumi T, Iwamoto M, Sando Y, Sugiura H, Asada N, Ennishi D, Tomida S, Fukuda-Kawaguchi E, Ishii Y, Maeda Y, Matsuoka KI.
Reduced dose of PTCy followed by adjuvant α-galactosylceramide enhances GVL effect without sacrificing GVHD suppression.
Sci Rep 11(1) 13125(2021) 34162921

Kuroishi T, Bando K, Bakti RK, Ouchi G, Tanaka Y, Sugawara S.
Migratory dendritic cells in skin-draining lymph nodes have nickel-binding capabilities.
Sci Rep 10(1) 5050(2020) 32193426

Saijou E, Enomoto Y, Matsuda M, Yuet-Yin Kok C, Akira S, Tanaka M, Miyajima A.
Neutrophils alleviate fibrosis in the CCl4-induced mouse chronic liver injury model.
Hepatol Commun 2(6) 703-717(2018) 29881822

Ueda K, Ikeda K, Ikezoe T, Harada-Shirado K, Ogawa K, Hashimoto Y, Sano T, Ohkawara H, Kimura S, Shichishima-Nakamura A, Nakamura Y, Shikama Y, Mori T, Mason PJ, Bessler M, Morishita S, Komatsu N, Shide K, Shimoda K, Koide S, Aoyama K, Oshima M, Iwama A, Takeishi Y.
Hmga2 collaborates with JAK2V617F in the development of myeloproliferative neoplasms.
Blood Adv 1(15) 1001-1015(2017) 29296743

Uchiyama R, Yonehara S, Taniguchi S, Ishido S, Ishii KJ, Tsutsui H.
Inflammasome and Fas-Mediated IL-1β Contributes to Th17/Th1 Cell Induction in Pathogenic Bacterial Infection In Vivo.
J Immunol 199(3) 1122-1130(2017) 28674179

Tanaka Y, Nagashima H, Bando K, Lu L, Ozaki A, Morita Y, Fukumoto S, Ishii N, Sugawara S.
Oral CD103-CD11b+ classical dendritic cells present sublingual antigen and induce Foxp3+ regulatory T cells in draining lymph nodes.
Mucosal Immunol 10(1) 79-90(2017) 27166558

Matsumoto T, Sasaki N, Yamashita T, Emoto T, Kasahara K, Mizoguchi T, Hayashi T, Yodoi K, Kitano N, Saito T, Yamaguchi T, Hirata K.
Overexpression of Cytotoxic T-Lymphocyte-Associated Antigen-4 Prevents Atherosclerosis in Mice.
Arterioscler Thromb Vasc Biol 36(6) 1141-51(2016) 27055906

Yamashita K, Kawata K, Matsumiya H, Kamekura R, Jitsukawa S, Nagaya T, Ogasawara N, Takano K, Kubo T, Kimura S, Shigehara K, Himi T, Ichimiya S.
Bob1 limits cellular frequency of T-follicular helper cells.
Eur J Immunol 46(6) 1361-70(2016) 27080143

Kiniwa T, Enomoto Y, Terazawa N, Omi A, Miyata N, Ishiwata K, Miyajima A.
NK cells activated by Interleukin-4 in cooperation with Interleukin-15 exhibit distinctive characteristics.
Proc Natl Acad Sci U S A 113(36) 10139-44(2016) 27551096

Yo M, Sakaue-Sawano A, Noda S, Miyawaki A, Miyoshi H.
Fucci-guided purification of hematopoietic stem cells with high repopulating activity.
Biochem Biophys Res Commun 457(1) 7-11(2015) 25534850

Masuko K, Wakita D, Togashi Y, Kita T, Kitamura H, Nishimura T.
Artificially synthesized helper/killer-hybrid epitope long peptide (H/K-HELP): preparation and immunological analysis of vaccine efficacy.
Immunol Lett 163(1) 102-12(2015) 25479286

Omi A, Enomoto Y, Kiniwa T, Miyata N, Miyajima A.
Mature resting Ly6C(high) natural killer cells can be reactivated by IL-15.
Eur J Immunol 44(9) 2638-47(2014) 24995967

Iwata A, Kawashima S, Kobayashi M, Okubo A, Kawashima H, Suto A, Hirose K, Nakayama T, Nakajima H.
Th2-type inflammation instructs inflammatory dendritic cells to induce airway hyperreactivity.
Int Immunol 26(2) 103-14(2014) 24150243

Mise-Omata S, Alles N, Fukazawa T, Aoki K, Ohya K, Jimi E, Obata Y, Doi T.
NF-κB RELA-deficient bone marrow macrophages fail to support bone formation and to maintain the hematopoietic niche after lethal irradiation and stem cell transplantation.
Int Immunol 26(11) 607-18(2014) 24908679

Nakashima K, Arai S, Suzuki A, Nariai Y, Urano T, Nakayama M, Ohara O, Yamamura K, Yamamoto K, Miyazaki T.
PAD4 regulates proliferation of multipotent haematopoietic cells by controlling c-myc expression.
Nat Commun 4 1836(2013) 23673621

Satoh T, Tajima M, Wakita D, Kitamura H, Nishimura T.
The development of IL-17/IFN-γ-double producing CTLs from Tc17 cells is driven by epigenetic suppression of Socs3 gene promoter.
Eur J Immunol 42(9) 2329-42(2012) 22674086

Tajima M, Wakita D, Satoh T, Kitamura H, Nishimura T.
IL-17/IFN-γ double producing CD8+ T (Tc17/IFN-γ) cells: a novel cytotoxic T-cell subset converted from Tc17 cells by IL-12.
Int Immunol 23(12) 751-9(2011) 22039016

Wada H, Kojo S, Kusama C, Okamoto N, Sato Y, Ishizuka B, Seino K.
Successful differentiation to T cells, but unsuccessful B-cell generation, from B-cell-derived induced pluripotent stem cells.
Int Immunol 23(1) 65-74(2011) 21135032

Inoue S, Noda S, Kashima K, Nakada K, Hayashi J, Miyoshi H.
Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells.
FEBS Lett 584(15) 3402-9(2010) 20600007

Mise-Omata S, Kuroda E, Sugiura T, Yamashita U, Obata Y, Doi TS.
The NF-kappaB RelA subunit confers resistance to Leishmania major by inducing nitric oxide synthase 2 and Fas expression but not Th1 differentiation.
J Immunol 182(8) 4910-6(2009) 19342670

Shimizu N, Noda S, Katayama K, Ichikawa H, Kodama H, Miyoshi H.
Identification of genes potentially involved in supporting hematopoietic stem cell activity of stromal cell line MC3T3-G2/PA6.
Int J Hematol 87(3) 239-45(2008) 18317883

Noda S, Horiguchi K, Ichikawa H, Miyoshi H.
Repopulating activity of ex vivo-expanded murine hematopoietic stem cells resides in the CD48-c-Kit+Sca-1+lineage marker- cell population.
Stem Cells 26(3) 646-55(2008) 18079432