Strain Information | |
---|---|
Image | |
BRC No. | RBRC00142 |
Type | Spontaneous Mutation Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Kit<W-v>/Rbrc |
Former Common name | C57BL/6-Kit<W-v>/+ |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | black [a/a B/B C/C +/+] gray with light belly, white spot, light tail an feet [a/a B/B C/C W/+] white with black eyes [a/a B/B C/C W/W] |
Strain development | Spontaneous mutation arosed in C57BL. |
Strain description | B6.Cg-Kit<W-v>. Viable dominant spotting. Spontaneous mutation arosed in C57BL. The Kit<W-v> mutation arose spontaneously in the C57BL strain. Heterozygote for Kit<W-v> are gray with light belly, white spot, light tail and feet. Homozygous mice are white with black eyes. The c-Kit cDNA from Kit<W-v>/Kit<W-v> mice showed an AC to T point mutation at nucleotide 2007 that resulted in the change from threonine to methionine at position 660. |
Colony maintenance | Sibling Mating (Heterozygote x Wild-type or Heterozygote) |
References | Mech. Dev., 108, 213-216 (2001). 11578878 Cancer Res., 52, 2304-2309 (1992). 1559233 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
---|---|
供与核酸 | |
Research application | Developmental Biology Research Immunology and Inflammation Research Mouse Models for Human Disease Neurobiology Research Reproductive Biology Research Sensorineural Research |
提供条件 | 条件を付加しない。 |
Depositor | 北村 幸彦(大阪大学) |
Strain Status | 凍結胚 |
Strain Availability | 凍結胚より作出したマウスを2~4ヶ月以内に提供可能 凍結胚を1ヶ月以内に提供可能 |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |