Strain Data Sheet

RBRC00141

Strain Information

Image
BRC No.RBRC00141
TypeSpontaneous Mutation Congenic
SpeciesMus musculus
Strain nameC57BL/6-Kit<W-37J>/Rbrc
Former Common nameC57BL/6-Kit<W-37J>
H-2 Haplotype
ES Cell line
Background strainC57BL/6
Appearanceblack
Strain development
Strain description
Colony maintenance
References
Incidence and distribution of experimental metastases in mutant mice with defective organ microenvironments (genotypes Sl/Sld and W/Wv).
Arguello F, Furlanetto R W, Baggs R B, Graves B T, Harwell S E, Cohen H J, Frantz C N
Cancer Res., 52, 2304-2309 (1992). 1559233

Health Report

Examination Date / Room / Rack2025/08/18Room:3-5Rack:D囮検査
2025/06/09Room:3-5Rack:D囮検査
2025/03/10Room:3-5Rack:D囮検査
2024/12/09Room:3-5Rack:D囮検査
2024/09/09Room:3-5Rack:D囮検査
2024/06/10Room:3-5Rack:D囮検査

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Kit
MGI:96677		KIT proto-oncogene receptor tyrosine kinase5Kit<W-37J>
MGI:1856241		dominant spotting 37 Jackson
  • acute myeloid leukemia(DisGeNET, MedGEN)

  • cutaneous mastocytosis(MedGEN)

  • gastrointestinal stromal tumor(DisGeNET, MedGEN)
    • more 3 Diseases
  • mastocytosis(DisGeNET)

  • piebaldism(DisGeNET, MedGEN)

  • testicular germ cell tumor(MedGEN)

    • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
  • absent coat pigmentation (MP:0005171)

  • decreased mast cell number (MP:0000336)

  • diluted coat color (MP:0000371)

  • irregular coat pigmentation (MP:0000372)

  • perinatal lethality, complete penetrance (MP:0011089)
    • more 3 phenotypes
  • polycythemia (MP:0002872)

  • prenatal lethality, incomplete penetrance (MP:0011101)

  • white spotting (MP:0002938)
    • Detailed phenotype data

    Ordering Information

    供与核酸
    Research applicationCancer Research
    Dermatology Research
    Developmental Biology Research
    Endocrine Deficiency Research
    Immunology and Inflammation Research
    Mouse Models for Human Disease
    Neurobiology Research
    Reproductive Biology Research
    提供条件条件を付加しない。
    Depositor北村　幸彦（大阪大学）
    Strain Status凍結胚のアイコン凍結胚
    Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
    凍結胚を1ヶ月以内に提供可能
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data