Strain Data Sheet

RBRC00141

Strain Information

Image
BRC No.RBRC00141
TypeSpontaneous Mutation Congenic
SpeciesMus musculus
Strain nameC57BL/6-Kit<W-37J>/Rbrc
Former Common nameC57BL/6-Kit<W-37J>
H-2 Haplotype
ES Cell line
Background strainC57BL/6
Appearanceblack
Strain development
Strain description
Colony maintenance
References
Incidence and distribution of experimental metastases in mutant mice with defective organ microenvironments (genotypes Sl/Sld and W/Wv).
Arguello F, Furlanetto R W, Baggs R B, Graves B T, Harwell S E, Cohen H J, Frantz C N
Cancer Res., 52, 2304-2309 (1992). 1559233

Health Report

Examination Date / Room / Rack2024/09/09Room:3-5Rack:D
2024/06/10Room:3-5Rack:D

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
KitKIT proto-oncogene receptor tyrosine kinase5Kitdominant spotting 37 Jackson
  • acute myeloid leukemia(DisGeNET, MedGEN)

  • cutaneous mastocytosis(MedGEN)

  • gastrointestinal stromal tumor(DisGeNET, MedGEN)
  • more 3 Diseases
  • mastocytosis(DisGeNET)

  • piebaldism(DisGeNET, MedGEN)

  • testicular germ cell tumor(MedGEN)
  • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • absent coat pigmentation(MP:0005171)

  • decreased mast cell number(MP:0000336)

  • diluted coat color(MP:0000371)

  • irregular coat pigmentation(MP:0000372)

  • perinatal lethality, complete penetrance(MP:0011089)
  • more 3 phenotypes
  • polycythemia(MP:0002872)

  • prenatal lethality, incomplete penetrance(MP:0011101)

  • white spotting(MP:0002938)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationCancer Research
    Dermatology Research
    Developmental Biology Research
    Endocrine Deficiency Research
    Immunology and Inflammation Research
    Mouse Models for Human Disease
    Neurobiology Research
    Reproductive Biology Research
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorYukihiko Kitamura (Osaka University)
    Strain Statusan icon for Live miceLive mice
    an icon for Frozen embryosFrozen embryos
    Strain AvailabilityCryopreserved embryos (within 1 month)
    Live mouse (1 to 3 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data