Strain Data Sheet

RBRC00140

Strain Information

Image
BRC No.RBRC00140
TypeSpontaneous Mutation Congenic
SpeciesMus musculus
Strain nameC57BL/6-JSR
Former Common nameC57BL/6-JSR
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearanceblack [a/a B/B C/C]
Strain developmentDeveloped by Dr. Shoji R., Institute for Developmental Research, Aichi Human Service Center, Japan. C57BL/6J background.
Strain descriptionB6.CTA-Jsr/IdrRbrc. Jsr, jumbled spine and ribs. Spontaneous mutation arose in CTA/Idr. Mutant mice show shortened trunk and kinky tail. Heterozygous mutant mice have shortened vertebrae. Homozygotes are viable. Jsr is located on Chr. 4 (79.9 cM)
Colony maintenanceSibling Mating (Heterozygote x Wild-type, Heterozygote)Mutant mice show shortened trunk and kinky tail. Homozygotes are viable.
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Jsr
MGI:96643		jumbled spine and ribs5Jsr
MGI:1859954		jumbled spine and ribs

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal vertebrae development(MP:0005225)

  • abnormal vertebrae morphology(MP:0000137)

  • abnormal vertebral arch development(MP:0005226)

  • decreased body length(MP:0001258)

  • decreased vertebrae number(MP:0004645)
    • more 12 phenotypes
  • kinked tail(MP:0000585)

  • kyphosis(MP:0000160)

  • lordosis(MP:0000162)

  • reduced fertility(MP:0001921)

  • rib fusion(MP:0000154)

  • scoliosis(MP:0000161)

  • short tail(MP:0000592)

  • short vertebral column(MP:0004704)

  • small caudal vertebrae(MP:0004652)

  • small vertebrae(MP:0004610)

  • thoracic vertebral fusion(MP:0004623)

  • vertebral fusion(MP:0004609)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorSatoshi Yonezawa (Aichi Human Service Center)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovery and QC required prior to distribution
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data