Strain Information | |
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Image | ![]() |
BRC No. | RBRC00134 |
Type | Spontaneous Mutation Congenic |
Species | Mus musculus |
Strain name | C57BL/6-Lyst<bg-J>/StmRbrc |
Former Common name | C57BL/6-bg/bg |
H-2 Haplotype | b |
ES Cell line | |
Background strain | C57BL/6J |
Appearance | light black [aaBBCC;bgJ/bgJ] |
Strain development | Jackson Laboratory - Aichi Cancer Center Research Institute (1973?) - Saitama Cancer Center (1977, F16). |
Strain description | Beige spontaneous mutant mice. Homozygous mutant mice snow a phenotype similar to human Chediak-Higashi syndrome. |
Colony maintenance | Homozygote x Homozygote |
References | Identification of the homologous beige and Chediak-Higashi syndrome genes. Barbosa M D, Nguyen Q A, Tchernev V T, Ashley J A, Detter J C, Blaydes S M, Brandt S J, Chotai D, Hodgman C, Solari R C, Lovett M, Kingsmore S F Nature, 382, 262-265 (1996). 8717042 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Lyst MGI:107448 | lysosomal trafficking regulator | 13 | Lyst<bg-J> MGI:1855969 | beige Jackson |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | more 19 phenotypes |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | |
Research application | Dermatology Research Hematological Research Immunology and Inflammation Research Internal/Organ Research Metabolism Research Mouse Models for Human Disease |
Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
Depositor | Hayase Shisa (Saitama Cancer Center) |
Strain Status | ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |