Strain Data Sheet

RBRC00113

Strain Information

Image
BRC No.RBRC00113
TypeSpontaneous Mutation Congenic
SpeciesMus musculus
Strain nameC3H/HeSn-Ttf/+tf
Former Common nameC3H/HeSn-Ttf/+tf
H-2 Haplotype
ES Cell line
Background strainC3H
Appearanceagouti, tail defects, tufted (A/A, T tf/+tf)
agouti, tufted (A/A, + tf/+tf)
Strain developmentC3H/HeSn-Ttf/+tf strain was introduced to National Institute of Genetics from the Jackson laboratory in 1985.
Strain descriptionT, Brachyury, semidominant, Chr 17. Discovered in a laboratory stock. T/T homozygous embryos die at 10 days of gestation due to failure to form a normal mesoderm. T/+ heterozygote have a shortened tail and abnormal sacral vertebrae. T/t mice are tailless. tf/tf homozygous mice show repeated waves of hair loss and regrowth. tf gene is linked to the T/t complex.
Colony maintenanceshort tail x normal tail
References

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Tbrachyury17Tbrachyury

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Itpr3inositol 1,4,5-triphosphate receptor 317Itpr3<tf>tufted

Ordering Information

供与核酸
Research applicationDermatology Research
Developmental Biology Research
提供条件条件を付加しない。
Depositor城石　俊彦（国立遺伝学研究所）
Strain Status凍結胚のアイコン凍結胚
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

BRC mice in Publications

Hatakeyama Y, Saito N, Mii Y, Takada R, Shinozuka T, Takemoto T, Naoki H, Takada S.
Intercellular exchange of Wnt ligands reduces cell population heterogeneity during embryogenesis.
Nat Commun 14(1) 1924(2023) 37024462