Strain Data Sheet

RBRC00093

Strain Information

Image
BRC No.RBRC00093
TypeInbred
SpeciesMus musculus
Strain nameC3H-fBi
Former Common name
H-2 Haplotypek
ES Cell line
Background strainC3H
Appearanceagouti, retinal degeneration [A/A Pde6brd1/Pde6brd1]
Strain development
Strain description
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Pde6b
MGI:97525		phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide5Pde6b<rd1>
MGI:1856373		retinal degeneration 1
  • congenital stationary night blindness autosomal dominant 2(DisGeNET, MedGEN)

  • retinitis pigmentosa 40(DisGeNET, MedGEN)

  • retinitis pigmentosa(DisGeNET)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • abnormal Muller cell morphology(MP:0005547)

  • abnormal ocular fundus morphology(MP:0002864)

  • abnormal optic disk morphology(MP:0008259)

  • abnormal photoreceptor outer segment morphology(MP:0003729)

  • abnormal retina morphology(MP:0001325)
    • more 11 phenotypes
  • abnormal retina outer nuclear layer morphology(MP:0003731)

  • absent photoreceptor outer segment(MP:0008585)

  • absent retina rod cells(MP:0008454)

  • blindness(MP:0002001)

  • decreased total retina thickness(MP:0011965)

  • decreased visual acuity(MP:0006149)

  • impaired pupillary reflex(MP:0006243)

  • retina degeneration(MP:0001326)

  • retina outer nuclear layer degeneration(MP:0008518)

  • thin retina outer nuclear layer(MP:0008515)

  • vision/eye phenotype(MP:0005391)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationSensorineural Research
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorHayase Shisa (Saitama Cancer Center)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data