Strain Data Sheet


Strain Information

BRC No.RBRC00073
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameBUS/Idr-bus
Former Common nameBUS/Idr-bus
H-2 Haplotype
ES Cell line
Background strainKYF
Appearancebrown agouti [A/A b/b C/C]
Strain developmentDeveloped by Satoshi Yonezawa, Institute for Developmental Research, Japan. Spontaneous mutation originally arosed in KYF/MsIdr-Jsr strain.
Strain descriptionbustling spontaneous mutation arose in Cdh23 gene. Homozygous mutant mice exhibit behavioral abnormalities such as hyperactivity, circling, head tossing and head tilting with vestibulocochlear defects. Viable and fertile, but it is difficult for homozygous female to nurse pups.
Colony maintenanceHeterozygote (female) x Homozygote (male) [or Crossing to BUS/Idr-+/+(RBRC00072)]
ReferencesHuman Mutation, 27, 88-97 (2006). 16281288
Acta Otolaryngol. Suppl., 519, 286-293 (1995). 7610888
Acta Otolaryngol. (Stockh), 116, 409-416 (1996). 8790740
Hear. Res., 134, 116-122 (1999). 10452381
Acta Otolaryngol., 117, 20-24 (1997). 9039475

Health Report

Examination Date / Room / Rack2024/02/26Room:4-BRack:K


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Cdh23cadherin 23 (otocadherin)10Cdh23<v-bus>bustling4930542A03Rik, ahl, ahl1, bob, mdfw, nmf112, nmf181, nmf252, USH1D

Ordering Information

Donor DNA
Research applicationNeurobiology Research
Sensorineural Research
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorSatoshi Yonezawa (Aichi Human Service Center)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Live mouse (3 to 6 months)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

BRC mice in Publications

No Data