Strain Data Sheet

RBRC00071

Strain Information

Image
BRC No.RBRC00071
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameBALB/cPas-Grm1<crv4>/PasRbrc
Former Common nameBALB/c-crv4
H-2 Haplotype
ES Cell line
Background strainBALB/cPas
Appearance
Strain development
Strain description
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Grm1glutamate receptor, metabotropic 110Grm1cerevelet 4
  • autosomal recessive spinocerebellar ataxia 13(DisGeNET, MedGEN)

  • spinocerebellar ataxia 44(MedGEN)
  • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • abnormal glomerular filtration barrier function(MP:0011856)

  • abnormal podocyte morphology(MP:0005326)

  • abnormal proximal convoluted tubule morphology(MP:0004756)

  • abnormal renal glomerulus basement membrane morphology(MP:0011348)

  • albuminuria(MP:0002871)
  • more 15 phenotypes
  • ataxia(MP:0001393)

  • decreased body size(MP:0001265)

  • glomerulosclerosis(MP:0005264)

  • increased brown adipose tissue amount(MP:0000005)

  • increased renal glomerulus basement membrane thickness(MP:0011409)

  • increased susceptibility to injury(MP:0005165)

  • kyphoscoliosis(MP:0000069)

  • male infertility(MP:0001925)

  • muscle spasm(MP:0000743)

  • narrow eye opening(MP:0005287)

  • nervous system phenotype(MP:0003631)

  • podocyte foot process effacement(MP:0008140)

  • reduced female fertility(MP:0001923)

  • renal cast(MP:0011402)

  • tremors(MP:0000745)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. * The RIKEN BRC shall maintain, store, multiply and distribute the BIOLOGICAL RESOURCE in Japan only.
    * Before any access to the biological resource, the Recipient will sign (as well as his/her administrative authority) the enclosed form to be sent to the Depositor (Institute Pasteur).
    * Prior to applications for a patent, or intellectual property or other rights based on the results of research using the BIOLOGICAL RESOURCE, the recipient shall discuss such applications with the DEPOSITOR. Use of the BIOLOGICAL RESOURCE shall be a collaborative research with the DEPOSITOR. The DEPOSITOR requires to be co-owner for the inventions or other intellectual property generated by using the BIOLOGICAL RESOURCE.
    DepositorJean-Louis Guenet (Institut Pasteur)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data