Strain Data Sheet

RBRC00005

Strain Information

Image
BRC No.RBRC00005
TypeCongenic
SpeciesMus musculus
Strain nameA.Cg-H2-T18<b>/Rbrc
Former Common nameA-Tlab
H-2 Haplotype
ES Cell line
Background strainA
Appearancealbino
Strain developmentMaintained by Toshitada Takahashi, Aichi Cancer Center Research Institute.
Strain descriptionMajor Histocompatibility complex (H2) congenic strain having a H2-T18<b> haplotype.
Colony maintenanceHomozygote x Homozygote
References
J. Natl. Cancer Inst., 31, 977-995 (1963). 14069836

Structure, function, and evolution of mouse TL genes, nonclassical class I genes of the major histocompatibility complex.
Y Obata, Y Satta, K Moriwaki, T Shiroishi, H Hasegawa, T Takahashi, N Takahata
Proc. Natl. Acad. Sci. USA, 91, 6589-6593 (1994). 8022824

Genetics in Wild Mice, 159-177 (1994). ISBN4762277746

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
H2-T18
MGI:95950		histocompatibility 2, T region locus 1817H2-T18<b> b variant

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • increased interferon-gamma secretion (MP:0008566)

  • intestinal inflammation (MP:0001858)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationCancer Research
    Immunology and Inflammation Research
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorToshitada Takahashi (Aichi Cancer Center)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data