Strain Data Sheet
RBRC-GD000108
Strain Information | |
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| Image | |
| BRC No. | RBRC-GD000108 |
| Type | Chemically-induced Mutation |
| Species | Mus musculus |
| Strain name | Tardbp<Rgsc02268> |
| Former Common name | M102268, RRM2Mut (F210I) |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | Mutant mouse strain established by RIKEN ENU-based gene-driven mutagenesis.Gene: Tardbp, Substitution: T→A |
| Colony maintenance | |
| References | EMBO J. 2018 Jun 1;37(11). 29764981 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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| Donor DNA | |
| Research application | |
| Specific Term and Conditions | The RECIPIENT of for-profit institution must contact the DEPOSITOR separately. The RECIPIENT of not for-profit institution must contact and discuss in good faith with the DEPOSITOR regarding inventorship, ownership, patent filing and licese fees and others, prior to filing a patent or make a contract with license fees with a third party for invention or products obtained from research results by using the BIOLOGICAL RESOURCES. |
| Depositor | Yoichi Gondo (RIKEN GSC) |
| Strain Status |  Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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Fratta P, Sivakumar P, Humphrey J, Lo K, Ricketts T, Oliveira H, Brito-Armas JM, Kalmar B, Ule A, Yu Y, Birsa N, Bodo C, Collins T, Conicella AE, Mejia Maza A, Marrero-Gagliardi A, Stewart M, Mianne J, Corrochano S, Emmett W, Codner G, Groves M, Fukumura R, Gondo Y, Lythgoe M, Pauws E, Peskett E, Stanier P, Teboul L, Hallegger M, Calvo A, Chiò A, Isaacs AM, Fawzi NL, Wang E, Housman DE, Baralle F, Greensmith L, Buratti E, Plagnol V, Fisher EM, Acevedo-Arozena A. Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis. EMBO J 37(11) (2018) 29764981 |