RBRC02849

Information1

Image
BRC No.RBRC02849
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.Cg-Ern1<tm1Dron>
Former Common nameIrel alpa knockout mouse +/- strain:129/C57BL/Black Swiss Webster
H-2 Haplotype
ES Cell line
Background strain
Appearanceblack [a/a B/B C/C]
Strain developmentMixed (129, B6 and Swiss Webster)Gene targeting was achieved in W4 ES cells
Strain descriptionHomozygous Ire1alpha- null mice are embryonic lethal
Colony maintenanceDiet for breeding is preferable but not essential.
ReferencesScience, 287, 664-666 (2000). 10650002
Nature, 415, 92-96 (2002). 11780124

Health Report

Examination Date / Room / Rack2010/07/05Room:4-5Rack:B
2010/05/10Room:4-5Rack:B
2010/03/08Room:4-5Rack:B
2009/11/09Room:4-5Rack:B
2009/09/07Room:4-5Rack:B

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Ern1endoplasmic reticulum (ER) to nucleus signaling 111Ern1<tm1Dron>targeted mutation 1, David Ron

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)11mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

供与核酸mouse Ern1 genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli Neomycin phosphotransferase
Research application
提供条件条件を付加する。利用者は事前に寄託者の提供承諾書を得る。
研究成果の公表にあたって寄託者の指定する文献を引用する。Science, 287, 664-666 (2000). Nature, 415, 92-96 (2002).
研究成果の公表にあたって謝辞の表明を必要とする。
DEPOSITOR hereby excludes any and all warranties, implied or express, including warranties of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE or of non-infringement of patents or other proprietary right. The sample of BIOLOGOCAL RESOURCE is provided "as is". In no event shall DEPOSITOR be liable for direct, indirect, special, incidental or consequential damages in connection with the BIOLOGICAL RESOURCE. RECIPIENT and RIKEN BRC will indemnify and hold DEPOSITOR harmless from any claims or liability resulting from the use of the BIOLOGICAL RESOURCE by you. Prior to filing an application for a patent, or intellectual property or other rights based on the results of research using the BIOLOGICAL RESOURCE, the recipient shall acquire the consent form the DEPOSITOR for such application.
DepositorDavid Ron(New York University School of Medicine)
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結精子を1ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data