RBRC01941

Information1

Image
BRC No.RBRC01941
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129-Nod2<tm1Jhgt>/GvnRbrc
Former Common nameCard15 KO (129/Ola background), 129-Card15<tm1>/GvnRbrc
H-2 Haplotype
ES Cell line
Background strain129
Appearance
Strain developmentINSERM・Marco Giovannini。PGK-hygromycinカセットは除去済み。
Strain descriptionCard15 (Nod2) 遺伝子のノックアウトマウス。エクソン1をEGFPカセットで置換。GFPの発現は低い。C57BL/6背景 (RBRC01869) 、C57BL/6と129混合背景 (RBRC01941) 。
Colony maintenanceHomozygote x Heterozygote, Homozygote
ReferencesPLoS ONE, 2, e523 (2007) 17565376

Health Report

Examination Date / Room / Rack2013/10/21Room:3-BRack:F
2013/08/26Room:3-BRack:F
2013/06/17Room:3-BRack:F
2013/04/15Room:3-BRack:F
2012/12/10Room:3-BRack:F
2012/10/15Room:3-BRack:F
2012/08/27Room:3-BRack:F
2012/06/18Room:3-BRack:F

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Nod2caspase recruitment domain family, member 158Nod2

Gene symbolGene nameChr.Allele symbolAllele namePromoter
GFPGreen Fluorescent Protein (Jellyfish)8

Gene symbolGene nameChr.Allele symbolAllele namePromoter
HBB2rabbit beta-globin polyA8HBB2

Information2

供与核酸Card 15 exon1 Knock-in EGFP, Rabbit beta-globin poly A
Research applicationInternal/Organ Research
Mouse Models for Human Disease
提供条件条件を付加する。
研究成果の公表にあたって謝辞の表明を必要とする。
RECIPIENT shall keep DEPOSITOR apprised of any results obtained from the BIOLOGICAL RESOURCE in the course of the research, as soon as they are available. Moreover, if the research results in a potential invention or a substance that may have potential commercial value (hereinafter referred as to the "Invention") RECIPIENT will promptly disclose this Invention to DEPOSITOR with samples thereof for DEPOSITOR's internal use.
RECIPIENT and DEPOSITOR will consult together and agree about the possibility of filing one or more patent application to Invention conceived by one or more employees of Recipients that directly arise out of the research. The Parties will negotiate in good faith the conditions of such patent application according to each party's inventiveness contribution in the Invention.
In case of such Invention, patentable or not, reduced in practice or developed in the course of the research that could not have been obtained, reduced to practice or developed but from using the Material and/or Confidential Information, RECIPIENT and DEPOSITOR shall confer with one another as regards licensing and commercialization of such Invention to negotiate in good faith the terms of an institutional agreement as regards said matters.
DepositorMarco Giovannini(INSERM)
Strain Status凍結精子のアイコン凍結精子
Strain Availability凍結精子より作出したマウスを2~4ヶ月以内に提供可能
凍結精子を1ヶ月以内に提供可能
Additional Info.Genotyping protocol -PCR-
GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC's MTA. Please also read Schedule B.

BRC mice in Publications

No Data